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Anti-inflammatory and osteoconductive multi-functional nanoparticles for the regeneration of an inflamed alveolar bone defect.
Biomater Sci
January 2025
Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Republic of Korea.
Infected alveolar bone defects pose challenging clinical issues due to disrupted intrinsic healing mechanisms. Thus, the employment of advanced biomaterials enabling the modulation of several aspects of bone regeneration is necessary. This study investigated the effect of multi-functional nanoparticles on anti-inflammatory/osteoconductive characteristics and bone repair in the context of inflamed bone abnormalities.
View Article and Find Full Text PDFEstablishment of a survival rabbit model for laryngotracheal stenosis: A prospective randomized study.
Laryngoscope Investig Otolaryngol
December 2024
National Engineering Research Center of Light Alloy Net Forming, State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai China.
Objective: To develop a reproducible survival rabbit model for laryngotracheal stenosis (LTS).
Methods: Seventy New Zealand white (NZW) rabbits were randomly divided into experimental groups ( = 30) and a control group ( = 40). In experimental groups, a nylon brush was inserted retrograde from the tracheotomy through the subglottis and rotated until a full layer circumferential mucosal injury to cartilage exposure, assisted by fiberoptic laryngoscopy (FOL) visualization.
Retreatment of a Failed Regenerative Endodontic Treatment in an Immature Tooth with a Horizontal Root Fracture: A Case Report.
Int J Clin Pediatr Dent
October 2024
Department of Endodontics, Galilee College of Dental Sciences, Nahariya; Azrieli Faculty of Medicine, Bar-Ilan University, Ramat Gan, Israel.
Unlabelled: Regenerative endodontic treatment (RET) has been suggested for the treatment of traumatized necrotic immature teeth. There are only a few reports of using RET to treat a horizontal root fracture. The aim of this paper is to describe successful regenerative retreatment in a tooth with a horizontal root fracture and dens invaginatus.
View Article and Find Full Text PDFEvaluating the potential of hydrophilic interaction liquid chromatography for collagen peptide mapping analysis.
J Chromatogr A
December 2024
Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, School of Pharmaceutical Sciences, Geneva, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU - Rue Michel Servet 1, Geneva, Switzerland. Electronic address:
This study presents a systematic approach for developing an innovative hydrophilic interaction liquid chromatography (HILIC) method for collagen peptide mapping analysis. The predominant post-translational modification (PTM) of collagen, proline hydroxylation, introduces polar hydroxyl groups throughout the collagen sequence, making HILIC a promising alternative to classical reversed-phase liquid chromatography (RPLC) approaches. This study employs sixteen model peptides, selected from in silico predicted tryptic peptides with zero missed cleavages and representing diverse physicochemical properties and structural motifs of collagen.
View Article and Find Full Text PDFEmergency autologous vein graft reconstruction after vascular closure device usage and subsequent infection.
BMJ Case Rep
November 2024
Vascular Surgery, Toronto General Hospital, Toronto, Ontario, Canada
Different techniques and devices can achieve haemostasis after endovascular procedures to reduce time to haemostasis and facilitate percutaneous large-bore access. One such device is the Angio-Seal, which accomplishes haemostasis by compressing a collagen plug against the arteriotomy. Multiple complications related to Angio-Seal exist, most commonly acute artery occlusions and rarely infections and endarteritis.
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