We report a very rare case of a paraganglioma arising from sellar and suprasellar region which has been treated with radiotherapy following multiple surgeries.
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Bilateral visual disturbances caused by a glomus vagale: illustrative case.
J Neurosurg Case Lessons
August 2023
1Department of Neurosurgery, Fundacion Santa Fe de Bogotá, Bogotá, Colombia.
Background: A glomus vagale tumor is an infrequent paraganglioma primarily characterized by auditory symptoms, cranial nerve involvement, or autonomic symptoms. However, visual involvement is not commonly observed, and to date, no cases have been reported in the literature.
Observations: The case involves a 62-year-old female patient with a history of right carotid body tumor resection.
Cushing syndrome due to ectopic ACTH secreting pheochromocytoma.
BMJ Case Rep
May 2022
Tabba Heart Institute, Karachi, Pakistan
In this case report, we present a case of a woman in her late 30s who presented with bilateral motor weakness, headache, hyperglycaemia and hypertension. Investigations revealed very high 24-hour urine cortisol of 90 524, ectopic adrenocorticotropic hormone secreting pheochromocytoma, normal metanephrine levels and empty sella, which has never been reported. CT chest and abdomen revealed enlarged left adrenal gland with large necrotic mass 4.
View Article and Find Full Text PDFMetastatic pheochromocytomas and paragangliomas (MPPGs) are rare endocrine malignancies that are associated with high rates of morbidity and mortality because of their large tumor burden and location, progression, and release of catecholamines. Systemic therapies for MPPGs are limited. MPPGs are characterized by pseudohypoxia that may prevent immune system recognition.
View Article and Find Full Text PDFRecurrent Primary Intrasellar Paraganglioma.
Case Rep Otolaryngol
June 2020
Department of Otolaryngology - Head and Neck Surgery, Indiana University School of Medicine, 1130 W. Michigan Street, Fesler Hall, Suite 400, Indianapolis, IN 46202, USA.
We describe a case of an 81-year-old male presenting with bitemporal visual field defects and blurry vision in the right eye. The patient was found to have a recurrent primary paraganglioma in the sellar and suprasellar region requiring a repeat transsphenoidal endoscopic resection. Immunohistochemical examination confirmed paraganglioma with the classic zellballen appearance which stained positive for chromogranin, synaptophysin, and S-100 in the periphery.
View Article and Find Full Text PDFPrimary Sellar Paraganglioma: Case Report with Literature Review and Immunohistochemistry Resource.
World Neurosurg
May 2019
Section of Neurosurgery, University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA. Electronic address:
Background: Differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Primary paraganglioma is seldom considered. We present a case of this unique pathology, review the relevant literature, and compile a compendium of immunohistochemical characteristics for use as a resource.
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