Eighty-five extended-spectrum beta-lactamase-producing Enterobacteriaceae from a Slovak hospital have been studied. SHV-2a was predominant, but other variants have been detected, namely, SHV-5, SHV-12, TEM-12, TEM-15, and TEM-132, which differed from TEM-1 by amino acid substitutions R164H, E240K, and I173V and had kinetic properties similar to those of TEM-28.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168689PMC
http://dx.doi.org/10.1128/AAC.49.7.3066-3069.2005DOI Listing

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