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In vitro activity of an oral streptogramin antimicrobial, XRP2868, against gram-positive bacteria. | LitMetric

In vitro activity of an oral streptogramin antimicrobial, XRP2868, against gram-positive bacteria.

Antimicrob Agents Chemother

Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.

Published: July 2005

The comparative in vitro potency of XRP2868, a new oral semisynthetic streptogramin antibiotic, was evaluated against gram-positive bacteria. XRP2868 inhibited all staphylococci at < or = 1 microg/ml and all non-pneumococcal streptococci at < or = 0.25 microg/ml and was fourfold more potent than quinupristin-dalfopristin against Staphylococcus aureus and Enterococcus faecium.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168641PMC
http://dx.doi.org/10.1128/AAC.49.7.3034-3039.2005DOI Listing

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