Compound efflux in Helicobacter pylori.

Antimicrob Agents Chemother

Infection Discovery, Cancer and Infection Research Area, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA.

Published: July 2005

Susceptibility testing with a variety of structurally unrelated compounds showed that hefC in Helicobacter pylori is involved in multidrug efflux. This efflux was shown to depend on the proton motive force, as demonstrated by ethidium bromide accumulation experiments. Thus, H. pylori contains an active multidrug efflux mechanism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168643PMC
http://dx.doi.org/10.1128/AAC.49.7.3009-3010.2005DOI Listing

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