Patients with severe bowel malabsorption do not have changes in iodine status.

Nutrition

Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

Published: September 2005

AI Article Synopsis

  • The study aimed to assess how intestinal malabsorption affects iodine levels in patients with short gut syndrome receiving total parenteral nutrition, compared to healthy controls and patients with normal digestion.
  • A total of 27 subjects were evaluated for iodine intake from food and nutrition solutions, along with measurements of urinary iodine excretion and other health markers.
  • Results showed no significant differences in iodine intake or excretion among the groups, indicating that dietary iodine in Brazil is adequate for maintaining iodine levels in patients with short gut syndrome.

Article Abstract

Objective: We evaluated the influence of intestinal malabsorption on iodine status in patients who had short gut syndrome and received total parenteral nutrition (group I) compared with control subjects who had eutrophia (group II) and patients who had other illnesses but normal digestive tracts (group III).

Methods: Twenty-seven subjects were studied. Iodine intake was determined by the measurement of iodine in ingested food and in parenteral nutrition solutions. Urinary iodine excretion was measured by the Sandell-Kalthoff reaction. Urinary creatinine, anthropometric, and thyroid hormone functions were also determined.

Results: Daily iodine intakes were 658 +/- 125 (mean +/- standard deviation), 573 +/- 204, and 629 +/- 208 microg for groups I, II, and III, respectively. Daily urinary iodine excretion levels were 399 +/- 308, 439 +/- 192, and 370 +/- 268 microg and ratios of urinary iodine (micrograms) to creatinine (grams) were 614 +/- 349, 354 +/- 142, and 483 +/- 292, respectively. There were no statistically significant differences across groups.

Conclusion: In Brazil the iodine provided by food, including iodized salt, has been sufficient to maintain iodine status in patients with short gut syndrome.

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Source
http://dx.doi.org/10.1016/j.nut.2005.02.006DOI Listing

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