Obesity is presently being combated by fitness regimens, drugs and diet. Increasing our understanding of the physiology of adipocytes, by deducing the regulatory pathways involved in lipid metabolism and all aspects of adipogenesis, will provide alternative strategies to reduce adverse problems of obesity. Research has suggested that mature fat cells may dedifferentiate to form proliferative-competent fat cell precursors. Knowledge of the dedifferentiation process will allow us to gain a solid grip on adipogenesis.
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http://dx.doi.org/10.1016/j.tice.2005.03.007 | DOI Listing |
Langmuir
January 2025
Physics Department, Lomonosov Moscow State University, Moscow 119991, Russian Federation.
The behavior of single linear chains on a substrate is a well-studied area of polymer science. Herein, one of the most essential issues is the interaction of the chains with the substrate, which determines both macromolecular conformations near the substrate and adhesive properties of polymer materials. However, very little is known about the effect of macromolecular architecture on adhesion.
View Article and Find Full Text PDFComput Biol Med
February 2025
Department of Mathematics, Capital University of Science and Technology, Islamabad, 44000, Pakistan.
The dynamic behavior of articular cartilage (a soft porous biological tissue) with strain-dependent nonlinear permeability under cyclic compressive loading and magnetic field is investigated computationally. The compressive force is applied on top surface of the cylindrical plug of the tissue by means of a porous filter. The study of mechanical and deformational behavior of soft porous tissues such as articular cartilage under dynamic compressive loading and magnetic field is useful in understanding the underlying mechano-biological process that may lead to the development of a treatment and recovery protocol in a diseased state.
View Article and Find Full Text PDFFront Public Health
December 2024
Department of Medicine, College of Health Sciences, Salale University, Fitche, Ethiopia.
Introduction: Diarrheal diseases are the top cause of preventable death, particularly among children under the age of five in developing countries like Ethiopia. Despite the national level of latrine coverage being 61%, diarrhea is responsible for the deaths of half a million children under 5 years annually. Therefore, this study aimed to assess diarrhea and its associated factors among children in open defecation free (ODF) and open defecation (OD) households of Degem district, Oromia, Ethiopia.
View Article and Find Full Text PDFBehav Res Methods
December 2024
Move'N'Brains Lab, Department of Psychology, University of Turin, Via Verdi, 10, 10124, Turin, Italy.
Aside from some common movement regularities, significant inter-individual and inter-trial variation within the same individual exists in motor system output. However, there is still a lack of a robust and widely adopted solution for quantifying the degree of similarity between movements. We therefore developed an innovative approach based on the Procrustes transformation to compute 'motor distance' between pairs of kinematic data.
View Article and Find Full Text PDFJPEN J Parenter Enteral Nutr
January 2025
Postgraduate Program in Health Science, Health Science Center, Federal University of Rio Grande do Norte, Natal, Brazil.
Background: This study aimed to investigate and propose novel approaches to calculate muscle quality index (MQI) using muscle mass derived from single-frequency bioelectrical impedance analysis (SF-BIA) and calf circumference in both unadjusted and body mass index (BMI)-adjusted forms. In addition, we examined their prognostic significance in patients with cancer.
Methods: A secondary analysis was conducted on a prospective cohort study of patients with cancer.
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