AI Article Synopsis
- A 30-year-old woman received a successful kidney transplant from her mother, with immediate urine output post-surgery.
- 24 hours later, she experienced a rapid decrease in urine volume and renal blood flow was diagnosed as accelerated acute rejection (AAR).
- Treatment involving plasma exchange and steroids led to significant improvement in her kidney function, maintaining healthy levels for 18 months.
Article Abstract
A 30-year-old female received living donor kidney transplantation from her mother. The surgical procedure was uneventfully performed and urine output was observed a few minutes after reperfusion. However, 24 hours after the surgery, the urine volume rapidly decreased with worsened renal blood flow as determined by Doppler ultrasonography, diagnosed as accelerated acute rejection (AAR). Plasma exchange (PE) combined with therapies including administration of steroids and OKT3 dramatically improved the renal status, resulting in maintenance of good renal function (serum Cr; 1.5 mg/dl) even after 18 months PE was considered as a powerful tool for AAR, and the literature was reviewed.
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