AI Article Synopsis
- Gitelman syndrome (GS) is an autosomal-recessive disorder that leads to low levels of potassium, magnesium, and calcium in the urine.
- A case study showed that during pregnancy, a patient with GS required six times the usual potassium and magnesium intake, but normal levels were not achieved even with IV supplementation.
- Despite these challenges, the pregnancy proceeded without any negative effects on the mother or baby's health, emphasizing the need for close monitoring of electrolytes rather than strictly aiming for normal blood levels.
Article Abstract
Gitelman syndrome (GS) is an autosomal-recessive condition characterized by hypokalaemia, hypomagnesaemia and hypocalciuria. Though it affects women of child-bearing age very little information is available about its impact on maternal and fetal outcome. We describe the course of pregnancy in a patient with GS which was characterized by a sixfold increase in potassium and magnesium requirements with inability to achieve normal levels despite intravenous supplementation. There was no adverse impact on the course of pregnancy or fetal outcome. The case highlights the variability in the phenotypic presentation of GS and recommends frequent monitoring of electrolytes with supplementation guided by clinical requirements without aiming to achieve normal blood levels.
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| http://dx.doi.org/10.1159/000086418 | DOI Listing |
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