Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Lamivudine and Adefovir Motif Variants Detected in chronic Hepatıtıs B patients.
Clin Ter
December 2016
Department of Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakır.
Background And Aims: Chronic hepatitis B is an important health problem worldwide. Lamivudine, adefovir, entecavir and telbivudine are the oral drugs licensed for the treatment of patients with chronic hepatitis B. Implementation of antiviral therapy leads to the emergence of mutant strains during the treatment in chronic hepatitis B.
View Article and Find Full Text PDF[Entecavir resistance in entecavir naive lamivudine treated chronic hepatitis B patients].
Mikrobiyol Bul
July 2009
Kocaeli Universitesi Tip Fakültesi Hastanesi, Merkez Laboratuvari, PCR Unitesi, Kocaeli.
Approved hepatitis B virus (HBV) therapies include interferon-alpha and nucleos(t)ide analogues. Lamivudine (LVD) is a nucleoside analogue and following long term LVD therapy, resistance emerges in a significant number of patients. Entecavir (ETV) is a novel deoxyguanosine analogue with potent activity against HBV in chronically infected patients.
View Article and Find Full Text PDFHepatitis B virus quantification and detection of YMDD mutants in a single reaction by real-time PCR and annealing curve analysis.
Antivir Ther
September 2008
NTU Center for Genomic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Background: Long-term antiviral therapy, although effective for treatment of hepatitis B, might select the emergence of drug-resistant hepatitis B virus (HBV) mutants. Detection of HBV mutants and determination of viral titre are two crucial parameters for monitoring treatment response and occurrence of mutants. In this study, we take lamivudine resistance as an example to develop a method that can determine both parameters in a single-tube PCR reaction.
View Article and Find Full Text PDFImplementation of antiviral therapy leads to the emergence of mutant strains during the treatment in chronic hepatitis B. Hepatitis B virus (HBV) with primary antiviral resistance may be rarely encountered. In this report, a chronic hepatitis B case who had never received adefovir dipivoxil but had primary adefovir resistance, was presented.
View Article and Find Full Text PDF[YVDD is the primary symbol of gene mutation in hepatitis B patients treated with lamivudine].
Zhonghua Gan Zang Bing Za Zhi
June 2005
Institute of Hepatology, The People's Hospital of Peking University, Beijing 100044, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!