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Valve Choice for TAVR: Much Left to re-SOLVE.

J Am Coll Cardiol

January 2025

Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland Ohio, USA.

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Article Synopsis
  • A major problem in fisheries governance is the lack of transparency regarding corporate ownership, particularly in the controversial practice of transshipment.
  • The study introduces a publicly accessible database that reveals ownership and operational details of 569 reefers, revealing that Russian and Chinese owners dominate the global fleet.
  • The findings indicate that improving transparency and governance in transshipment could be achieved through collaboration among vessel owners, flag states, and fishing regulators.
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Background: Cerebral embolic protection devices (EPDs) were developed to mitigate the risk of stroke during transcatheter aortic valve replacement (TAVR), but their benefit remains unproven. In the PROTECTED-TAVR trial (Stroke Protection With Sentinel During Transcatheter), EPD use did not reduce periprocedural stroke (primary study outcome) but led to a 62% reduction in the secondary end point of disabling stroke. Given these results, the impact of EPDs during TAVR remains unclear.

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