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Forward-backward translation, content validity, face validity, construct validity, criterion validity, test-retest reliability, and internal consistency of a questionnaire on patient acceptance of orthodontic retainer.
PLoS One
January 2025
Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, Universiti Malaya (UM), Kuala Lumpur, Malaysia.
This study aimed to assess the validity and reliability of a questionnaire on patient acceptance of orthodontic retainers. The original questionnaire was forward- and backward-translated, followed by four validity tests (content validity, face validity, construct validity, criterion validity) and two reliability tests (test-retest reliability, internal consistency). Content validity was assessed by nine orthodontists who appraised the questionnaire's representativeness, relevance, clarity, and necessity.
View Article and Find Full Text PDFImage segmentation with traveling waves in an exactly solvable recurrent neural network.
Proc Natl Acad Sci U S A
January 2025
Department of Mathematics, Western University, London, ON N6A 3K7, Canada.
We study image segmentation using spatiotemporal dynamics in a recurrent neural network where the state of each unit is given by a complex number. We show that this network generates sophisticated spatiotemporal dynamics that can effectively divide an image into groups according to a scene's structural characteristics. We then demonstrate a simple algorithm for object segmentation that generalizes across inputs ranging from simple geometric objects in grayscale images to natural images.
View Article and Find Full Text PDFComprehensive characterization of the transcriptional landscape in Alzheimer's disease (AD) brains.
Sci Adv
January 2025
Department of Biostatistics and Health Data Science, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Alzheimer's disease (AD) is the leading dementia among the elderly with complex origins. Despite extensive investigation into the AD-associated protein-coding genes, the involvement of noncoding RNAs (ncRNAs) and posttranscriptional modification (PTM) in AD pathogenesis remains unclear. Here, we comprehensively characterized the landscape of ncRNAs and PTM events in 1460 samples across six brain regions sourced from the Mount Sinai/JJ Peters VA Medical Center Brain Bank Study and Mayo cohorts, encompassing 33,321 long ncRNAs, 92,897 enhancer RNAs, 53,763 alternative polyadenylation events, and 900,221 A-to-I RNA editing events.
View Article and Find Full Text PDFpyAKI-An open source solution to automated acute kidney injury classification.
PLoS One
January 2025
Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Müunster, Müunster, Germany.
Objective: Acute kidney injury (AKI) is a frequent complication in critically ill patients, affecting up to 50% of patients in the intensive care units. The lack of standardized and open-source tools for applying the Kidney Disease Improving Global Outcomes (KDIGO) criteria to time series, requires researchers to implement classification algorithms of their own which is resource intensive and might impact study quality by introducing different interpretations of edge cases. This project introduces pyAKI, an open-source pipeline addressing this gap by providing a comprehensive solution for consistent KDIGO criteria implementation.
View Article and Find Full Text PDFThe privacy protection of the internet of vehicles resource transaction details based on blockchain.
PLoS One
January 2025
Yunnan Tengjian Technology Co., Ltd, Kunming, China.
The rapid development of Internet of Things technology has promoted the popularization of Internet of Vehicles, and its safety and reliability have become the focus of intelligent transportation system research. Vehicle-road collaboration relies on the collaborative computing and storage resources of the vehicle on-board unit (OBU), which are usually limited. When the vehicle in the edge area needs to do computing tasks such as intelligent driving, but its own computing resources are insufficient.
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