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What's New in Cirrhotic Cardiomyopathy?-Review Article.
J Pers Med
December 2021
Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Cirrhotic cardiomyopathy (CCM) is a relatively new medical term. The constant development of novel diagnostic and clinical tools continuously delivers new data and findings about this broad disorder. The purpose of this review is to summarize current facts about CCM, identify gaps of knowledge, and indicate the direction in which to prepare an updated definition of CCM.
View Article and Find Full Text PDFEffects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.
Front Physiol
March 2021
Department of Cardiology, Fujian Provincial Hospital, Provincial Clinical Medicine College of Fujian Medical University, Fuzhou, China.
Aim: The aim was to study the effect of Allitridum (Allicin) on the heterologous expression of the late sodium current on the ΔKPQ-SCN5A mutations in HEK293 cells, with a view to screening new drugs for the treatment of long QT syndrome type 3 (LQT3).
Methods And Results: The ΔKPQ-SCN5A plasmid was transiently transferred into HEK293 cells by liposome technology and administered by extracellular perfusion, and the sodium current was recorded by whole-cell patch-clamp technology. Application of Allicin 30 μM reduced the late sodium current ( ) of the Nav1.
Implantable Cardioverter-defibrillators for Primary Prevention in Pediatric Patients: What's Next?
J Innov Card Rhythm Manag
September 2018
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Inappropriate automatic mode switching episodes: What's the mechanism?
J Electrocardiol
March 2019
Department of Cardiology, Hospital Universitario Fundación Jiménez Díaz-Quironsalud, Universidad Autónoma de Madrid, Madrid, Spain.
We present a case series of five patients reporting abnormal automatic mode switching (AMS) episodes during routinary cardiac defibrillator (ICD) and pacemaker (PM) follow-up. This non-previously described phenomenon was reported to St. Jude Medical (Abbott) Technical Support that confirmed the inappropriate automatic mode switching.
View Article and Find Full Text PDFWhat’s hot today? Current topics in sports and exercise medicine.
Br J Sports Med
January 2013
UNC Department of Orthopaedics and Emergency Medicine, UNC School of Medicine, UNC Chapel Hill, North Carolina 27599, USA.
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