Immunohistochemistry and virus isolation were performed on 1,057 birds. Immunohistochemistry, virus isolation, or both found 325 birds to be West Nile virus positive. Of these, 271 were positive by both methods. These results indicate that virus isolation and immunohistochemistry are approximately equal in their ability to detect West Nile virus.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151906 | PMC |
http://dx.doi.org/10.1128/JCM.43.6.2904-2908.2005 | DOI Listing |
Routine use of genetic data in healthcare is much-discussed, yet little is known about its performance in epidemiological models including traditional risk factors. Using severe COVID-19 as an exemplar, we explore the integration of polygenic risk scores (PRS) into disease models alongside sociodemographic and clinical variables. PRS were optimized for 23 clinical variables and related traits previously-associated with severe COVID-19 in up to 450,449 UK Biobank participants, and tested in 9,560 individuals diagnosed in the pre-vaccination era.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Anesthesiology, Medical Faculty, Heidelberg University, 69120, Heidelberg, Germany.
Invasive infections with Aspergillus fumigatus in ICU patients are linked to high morbidity and mortality. Diagnosing invasive pulmonary aspergillosis (IPA) in non-immunosuppressed patients is difficult, as Aspergillus antigen (galactomannan [GM]) may have other causes. This retrospective study analyzed 160 ICU surgical patients with positive GM in broncho-alveolar lavage fluid (BALF), classifying them based on AspICU criteria for suspected IPA (pIPA) or aspiration.
View Article and Find Full Text PDFSci Rep
January 2025
Institute of Mathematical Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
A dynamics informed neural networks (DINNs) incorporating the susceptible-exposed-infectious-recovered-vaccinated (SEIRV) model was developed to enhance the understanding of the temporal evolution dynamics of infectious diseases. This work integrates differential equations with deep neural networks to predict time-varying parameters in the SEIRV model. Experimental results based on reported data from China between January 1, and December 1, 2022, demonstrate that the proposed dynamics informed neural networks (DINNs) method can accurately learn the dynamics and predict future states.
View Article and Find Full Text PDFSci Rep
January 2025
Institute for Research on Population and Social Policies, National Research Council of Italy, 00185, Rome, Italy.
Social withdrawal is a widespread phenomenon among adolescents, presenting significant challenges in understanding its aetiology and dynamics. This study, drawing on data from two cross-sectional surveys conducted in 2019 and 2022 on students in public upper secondary schools, investigates the trend of self-isolation among Italian adolescents before and after the COVID-19 pandemic. The two nationally representative samples comprise 3273 and 4288 participants, respectively, with 46.
View Article and Find Full Text PDFSci Adv
January 2025
Thomas Lord Department of Mechanical Engineering and Materials, Duke University, Durham, NC 27708, USA.
Precise and rapid disease detection is critical for controlling infectious diseases like COVID-19. Current technologies struggle to simultaneously identify viral RNAs and host immune antibodies due to limited integration of sample preparation and detection. Here, we present acoustofluidic integrated molecular diagnostics (AIMDx) on a chip, a platform enabling high-speed, sensitive detection of viral immunoglobulins [immunoglobulin A (IgA), IgG, and IgM] and nucleic acids.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!