Tracheal reaction to three different intraluminal stents in an animal model of tracheomalacia.

J Laparoendosc Adv Surg Tech A

Department of Pediatric Surgery, Dana Children's Hospital, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Published: June 2005

AI Article Synopsis

  • Three different internal airway stents were tested in an animal model for treating tracheomalacia: the Palmaz and NIR stents (both stainless steel) and the Nitinol stent (made of nickel-titanium in a spiral shape).
  • All three stents could be effectively stabilized in affected areas of the trachea.
  • The Nitinol stent showed better biocompatibility with less tissue reaction and easier extraction, making it a promising option for treating tracheo- and bronchomalacia.

Article Abstract

Three different internal airway stents were studied in an animal model of tracheomalacia: the Palmaz stent (Johnson & Johnson, Warren, New Jersey) and the NIR stent (Medinol Ltd., Tel Aviv, Israel)--both made of stainless steel in the form of tubular mesh--and the Nitinol stent, made of nickel-titanium formed into a spiral shape. All three stents could be adequately stabilized in the malacic tracheal segment. The Nitinol stent (Medinol Ltd., Tel Aviv, Israel) proved to be less reactive to the tracheal mucosa, demonstrated higher biocompatibility with significantly less granulation tissue formation, and showed superior radial resistance. Extraction of the Nitinol stent also proved to be much smoother. This stent may be the stent of choice in the treatment of tracheo- and bronchomalacia.

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http://dx.doi.org/10.1089/lap.2005.15.333DOI Listing

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