The study of adhesion has received considerable attention in recent years, partly due to advances in the design and fabrication of micro/nano devices. Many adhesion investigations are centered on single-spherical-contact models, which include the classic Johnson-Kendall-Roberts (JKR), improved Derjaguin-Muller-Toporov (IDMT), and Maugis-Dugdale (MD) models. Based on the IDMT single-asperity model, adhesive rough surface contact models have also been developed, which are valid for elastic and elastic-plastic contact conditions. A limitation of the IDMT-based models is that they are only valid for application cases with low adhesion parameter values. In this research, a contacting rough surface adhesion model was developed by combining an extended Maugis-Dugdale (EMD) model (which is only valid for elastic contacts) with an IDMT-based elastic-plastic adhesion model. The proposed model, termed the elastic-plastic hybrid adhesion model, is valid for the entire adhesion parameter range and also for elastic-plastic contacts. The proposed model gives results similar to the EMD rough surface model when the contact is primarily elastic. Moreover, the proposed model was compared to an IDMT-based model (ISBL model) and both gave similar results for contacts with low adhesion parameter values. With high adhesion parameter values, the ISBL model fails, whereas the proposed model correctly predicts higher adhesion. Last, based on the stiffness of the external force, the instability for adhesive rough surfaces in contact was also discussed, and it was postulated that a high peak value of the external force stiffness directly relates to the unstable contact process.
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http://dx.doi.org/10.1016/j.jcis.2005.04.058 | DOI Listing |
Front Biosci (Landmark Ed)
January 2025
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, 401336 Chongqing, China.
Background: Myocardial ischemia-reperfusion (I/R) injury and coronary microcirculation dysfunction (CMD) are observed in patients with myocardial infarction after vascular recanalization. The antianginal drug trimetazidine has been demonstrated to exert a protective effect in myocardial ischemia-reperfusion injury.
Objectives: This study aimed to investigate the role of trimetazidine in endothelial cell dysfunction caused by myocardial I/R injury and thus improve coronary microcirculation.
Pharmaceutics
January 2025
Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Background/objectives: Leukocytes play a significant role in both acute kidney injury (AKI) and chronic kidney disease (CKD), contributing to pathogenesis and tissue damage. The process of leukocyte infiltration into the inflamed tissues is mediated by the interactions between the leukocytes and cell adhesion molecules (CAMs, i.e.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Chemistry and Chemical Technology, Manash Kozybayev North Kazakhstan University, Petropavlovsk 150000, Kazakhstan.
The aim of the work was to study the effect of additive concentration on changes in the adhesive and cohesive strength of bitumen. To evaluate the effectiveness of modifiers in the composition of binary and triple bitumen systems in relation to mineral fillers of two grades, the method of determination of the adhesive efficiency and thermodynamic calculations of adhesion and cohesion work were used. The following compounds were used as additives: synthesized from the oil refining waste and (waste sealing liquid).
View Article and Find Full Text PDFPathogens
January 2025
Biomedical Sciences Laboratory (CBMU), School of Medicine, Universidad de Los Andes, Bogotá D.C 111711, Colombia.
, the etiological agent of Chagas disease, is a parasite known for its diverse genotypic variants, or Discrete Typing Units (DTUs), which have been associated with varying degrees of tissue involvement. However, aspects such as parasite attachment remain unclear. It has been suggested that the TcI genotype is associated with cardiac infection, the most common involved site in chronic human infection, while TcII is associated with digestive tract involvement.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, China.
This paper proposes a hierarchical framework-based solution to address the challenges of vehicle state estimation and lateral stability control in four-wheel independent drive electric vehicles. First, based on a three-degrees-of-freedom four-wheel vehicle model combined with the Magic Formula Tire model (MF-T), a hierarchical estimation method is designed. The upper layer employs the Kalman Filter (KF) and Extended Kalman Filter (EKF) to estimate the vertical load of the wheels, while the lower layer utilizes EKF in conjunction with the upper-layer results to further estimate the lateral forces, longitudinal velocity, and lateral velocity, achieving accurate vehicle state estimation.
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