This review examines the evidence for some of the common psychological complications found across the life span of patients with sickle cell disease (SCD), which are likely to be encountered by haematologists responsible for their medical management. Electronic searches of medical and psychological databases were conducted with a focus on three main areas: psychological coping, quality of life and neuropsychology. Psychological complications were identified in both children and adults with SCD, and included inappropriate pain coping strategies; reduced quality of life owing to restrictions in daily functioning, anxiety and depression; and neurocognitive impairment. There were wide variations in design and consistency of the studies, therefore, some caution needs to be observed in the findings. Moreover, interventional studies were lacking in some areas such as neuropsychology. Utilization of psychological interventions including patient education, cognitive behavioural therapy, and special educational support to help improve the quality of life of patients are recommended.
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http://dx.doi.org/10.1111/j.1365-2141.2005.05500.x | DOI Listing |
Clin Oral Investig
January 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Objectives: This study investigates the clinical and patient-reported outcomes of full-endoscopic parotidectomy compared to the conventional approach.
Methods: Between July 2021 and December 2023, patients who underwent parotidectomy were prospectively enrolled and assigned to either the full-endoscopic parotidectomy group (Group I) or the conventional surgery group (Group II). Clinical outcomes were evaluated, and patient-reported outcomes were assessed using a Visual Analogue Scale and five FACE-Q scales.
Nurs Health Sci
March 2025
Department of Neurology, The Third People's Hospital of Cheng Du, Chengdu, China.
To explore the level and influencing factors of caregivers' benefit finding in stroke patients from both the patient and caregiver perspectives. The growing number of stroke patients with physical impairments has presented significant challenges for caregivers. Benefit finding refers to the positive experience caregivers derive from their caregiving roles, which can help mitigate the adverse effects on their mental health.
View Article and Find Full Text PDFPLoS One
January 2025
Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Irritable Bowel Syndrome (IBS) patients and Somatization Symptom Disorder (SSD) patients experience somatization symptoms relative to their corresponding processes. IBS patients may also have a diagnosis of both IBS and SSD. Somatization symptoms cause significant psychological, emotional and social distress.
View Article and Find Full Text PDFNeuropsychopharmacol Hung
December 2024
Department of Pharmacodynamics, Faculty of Pharmaceutical Sciences, Semmelweis University, Budapest, Hungary.
Background: Major depressive disorder (MDD) is a complex psychiatric condition significantly impacted by environmental stress and inflammation. Previous research suggests that stress-induced alterations in the blood-brain barrier (BBB) may allow pro-inflammatory cytokines like interleukin-6 (IL-6) to enter the brain, contributing to depression. Tumor necrosis factor-alpha (TNF-α) is another prominent cytokine implicated in depression, but its role in the context of BBB integrity and stress-mediated depression remains unclear.
View Article and Find Full Text PDFInt J Nurs Knowl
January 2025
Health Sciences Department, Public University of Navarre (UPNA), Pamplona, Spain.
Purpose: This study aimed to establish the content validity of the proposed nursing diagnosis (ND) "Adult Disuse Syndrome" and all its components.
Method: This is an exploratory descriptive study of diagnostic content validation under Fehring's proposal. Forty three expert nurses with clinical, teaching, and research experience analyzed the components of the diagnosis.
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