AI Article Synopsis
- - The study aimed to analyze the presence of SARS-CoV RNA in the blood and excretion of patients who had recovered from SARS for better understanding and treatment of the virus.
- - Researchers tested 276 samples (plasma, urine, feces, sputum) from 23 convalescent patients, discovering that about 39% tested positive for SARS-CoV RNA, primarily in feces and sputum, but none were found in plasma or urine.
- - The findings suggest that some recovered patients still excrete SARS-CoV RNA, highlighting the need for careful handling of excretions to prevent possible re-transmission of the virus.
Article Abstract
Objective: To examine the RNA of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in the blood and excretion of convalescent patient with SARS for prevention and treatment of the disease.
Methods: A total of 276 samples, including plasma, urine, feces and sputum, obtained from 23 convalescent patients with SARS were studied at 3 time-points at least 21 days after the onset of symptoms. RNA was extracted and nested reverse transcription-polymerase chain reaction (RT-PCR) was carried out using SARS-CoV specific primers.
Results: Among the 276 samples, SARS-CoV RNA was detected in 6 cases (38.8%) by nested RT-PCR. The positive rates of SARS-CoV RNA was 5.8% in feces and 2.9% in sputum samples but SARS-CoV RNA was not detectable in plasma and urine of all the cases.
Conclusion: The existence of SARS-CoV RNA in the excretion of some convalescent patients with SARS showed that the excretion from these patients should be carefully treated whilthe re-transmission of SARS by which, should be further studied.
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