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Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwelling older adults.
BMJ Open
January 2025
Department of General Practice, University College Cork, Cork, Ireland
Objectives: To describe the prevalence of sub-optimal monitoring for selected higher-risk medicines in older community-dwelling adults and to evaluate patient characteristics and outcomes associated with sub-optimal monitoring.
Study Design: Retrospective observational study (2011-2015) using historical general practice-based cohort data and linked dispensing data from a national pharmacy claims database.
Setting: Irish primary care.
Racial and ethnic discrimination and DSM-5 substance use disorders among U.S. adults.
J Stud Alcohol Drugs
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.
Objective: Racial and ethnic discrimination is a risk factor for substance use among United States adults. However, whether discrimination is associated with substance use disorders (SUDs) overall and by race and ethnicity is less understood.
Methods: We used data from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (n=35,355) and defined past-year discrimination as a summary scale (range: 0-4).
Mental health outcomes, associated factors, and coping strategies among LGBTQ adolescent and young adults during the COVID-19 pandemic: A systematic review.
J Psychiatr Res
December 2024
School of Osteopathic Medicine, Rowan-Virtua School of Osteopathic Medicine, Stratford, NJ, USA.
LGBTQ adolescents and young adults have been disproportionately affected by the COVID-19 pandemic. This review aims to describe the impact of the COVID-19 crisis on mental health among LGBTQ adolescents and young adults, identify associated factors, and summarize coping strategies. A systematic review was conducted by searching six databases (PubMed, Embase, PsycINFO, CINAHL, Web of Science, MEDLINE).
View Article and Find Full Text PDFRandomised, placebo-controlled, double-blinded, four-way crossover trial to demonstrate the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for adrenal insufficiency in a healthy population: the STARLIT-2 study protocol.
BMJ Open
December 2024
Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK
Introduction: Cortisol is an essential stress hormone and failure of its production, known as adrenal insufficiency (AI), is associated with significant mortality due to adrenal crisis. The Short Synacthen Test (SST) is the current diagnostic test of choice for AI, but it is both invasive and resource intensive. Globally, there is an unmet need for a non-invasive, cost-effective test.
View Article and Find Full Text PDFRisk Factors of Post-Tonsillectomy Bleeding and Differences Between Children and Adults: Implications for Risk Assessment.
Turk Arch Otorhinolaryngol
January 2025
Private Clinic, Department of Otorhinolaryngology-Head and Neck Surgery, Ankara, Türkiye.
Objective: To investigate the association between clinical factors and post-tonsillectomy hemorrhage (PTH) including rebleeding episodes.
Methods: The medical records of 1,082 patients who underwent tonsillectomy between May 2018 and April 2019 were reviewed. The entire study cohort included 431 (39.
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