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The impact of anxiety and mood disorders on physical disease: the worried not-so-well. | LitMetric

The impact of anxiety and mood disorders on physical disease: the worried not-so-well.

Curr Psychiatry Rep

Department of Psychiatry, Jefferson Medical College, 1518 Walnut Street, Suite 1110, Philadelphia, PA 19102, USA.

Published: June 2005

AI Article Synopsis

  • Depression and anxiety can worsen chronic physical illnesses, leading to higher rates of illness and death, particularly in conditions like gastrointestinal disorders, cancer, and heart disease.
  • Behavioral factors, such as unhealthy lifestyle choices and poor sleep, as well as biological factors, like heightened inflammation, contribute to this negative relationship.
  • The recent literature highlights these interconnected issues and emphasizes the need for addressing mental health in patients with chronic diseases.

Article Abstract

Depression and anxiety can adversely affect the course of chronic physical illnesses, increasing morbidity and mortality. The literature during the past year is reviewed for gastrointestinal disorders, cancer, pain, heart disease, diabetes, and pulmonary disease. Causes for this relationship are behavioral and biological. Behavioral factors in patients with depressive and anxiety disorders include unhealthy lifestyle choices, disrupted sleep, and poor adherence to medical regimens. Biological mechanisms include increased inflammatory response and disruption of the hypothalamic-pituitary-adrenal axis.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11920-005-0055-yDOI Listing

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