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[A Case of Intestinal Metastasis of Testicular Choriocarcinoma Revealed Through Gastrointestinal Bleeding].
Hinyokika Kiyo
November 2024
The Department of Urology, Hiroshima Prefectural Hospital.
A 26-year-old male presented to a hospital with complaints of hemoptysis and right scrotal swelling. Computed tomography (CT) revealed right testicular swelling, multiple lung metastases, and small intestinal wall thickening. The patient's β-human chorionic gonadotropin, alpha-fetoprotein, lactate dehydrogenase, and hemoglobin levels were 103.
View Article and Find Full Text PDFEpithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases.
Hum Pathol
November 2024
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Electronic address:
Article Synopsis
- Epithelioid trophoblastic tumor (ETT) is a rare type of tumor found in the testis, with only seven cases documented before this study, which adds five more cases from a single institution, making it the largest series reported.
- The patients had a mean age of 44, and most had prior testicular germ cell tumors treated with chemotherapy; ETT appeared in metastatic sites many years later, and its diagnosis was often associated with unusual histological features that can resemble other types of cancer.
- Despite treatment, the outcomes were poor, with two patients dying within 17 months of diagnosis and three others remaining alive with metastatic disease averaging 20 months post-diagnosis, highlighting the aggressive nature of ETT.
Navigating Diagnostic Challenges: Primary Pulmonary Choriocarcinoma Depicted by Fluorodeoxyglucose (FDG)-Positron Emission Tomography-Computed Tomography (PET/CT).
Cureus
September 2024
Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Amman, JOR.
This report explores a noteworthy case diagnosed with primary pulmonary choriocarcinoma (PPC), a rare and often fatal non-seminomatous germ cell tumor. Initially misdiagnosed as lung adenocarcinoma, this case underscores the diagnostic complexities associated with PPC. A 44-year-old woman initially misdiagnosed with non-small lung cancer underwent unsuccessful chemoradiation.
View Article and Find Full Text PDFA case report on renal metastasis as an unusual presentation of choriocarcinoma.
BMC Womens Health
October 2024
Department of Gynecology and Obstetrics, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R. China.
Article Synopsis
- * The case presented involves a 27-year-old woman with symptoms like vaginal bleeding and abdominal pain, suspected to be linked to an ectopic pregnancy, but tests revealed no signs of pregnancy during surgeries.
- * After multiple treatments that failed to diagnose the issue, her hCG levels rose significantly, leading to emergency surgery and subsequent imaging that revealed suspicious lesions in her kidneys and lungs, confirming the advanced progression of the disease.
SEVERE DISEASE PROGRESSION OF POSTMOLAR GESTATIONAL NEOPLASM IN A VIETNAMESE YOUNG FEMALE PATIENT AFTER TREATMENT REFUSAL: INSIGHTS FROM A CASE REPORT AND LITERATURE REVIEW.
Exp Oncol
October 2024
Tu Du Clinical Research Unit, Tu Du Hospital, Ho Chi Minh City, Vietnam.
Article Synopsis
- - Choriocarcinoma is a highly aggressive but treatable form of gestational trophoblastic neoplasm, which can lead to severe health issues, including massive hemorrhage and death, particularly in women of childbearing age with high-risk scores.
- - A case study highlights a 20-year-old woman with widespread metastatic choriocarcinoma who lapsed in treatment due to the COVID-19 pandemic, resulting in severe complications like intraabdominal hemorrhage that required immediate surgery.
- - Despite being in a coma and on a ventilator, the patient successfully underwent multiagent chemotherapy, initially with the EMA/CO regimen followed by the TP/TE regimen, leading to a significant decrease in her β-hCG levels,
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