Purpose Of Review: This paper reviews the recent literature on the management of malignant large airway obstruction using interventional pulmonology techniques.
Recent Findings: A number of interventional techniques have been developed during the last 25 years. Recent papers expand on this work, reaffirming the utility of laser bronchoscopy; introducing newer, less expensive technologies with similar outcomes; and attesting to the benefit of airway stenting. Electrocautery is likely to replace laser as the preferred tool for coagulation of intrinsic airway tumors because it is readily available in most hospitals and is much less expensive to set up. Several large series have attested to the excellent results achieved with airway stents placed to relieve extrinsic large airway obstruction. Investigators are using new technologies in an attempt to predict the proper location of stent placement to achieve maximum palliation of symptoms. Published guidelines are available describing the application of interventional techniques.
Summary: A number of interventional pulmonology techniques are available to treat large airway obstruction from malignant tumor. Clinical studies and personal experience attest to their utility. More evidenced-based studies are needed to help determine the best technique for a particular type of obstruction.
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http://dx.doi.org/10.1097/01.mcp.0000166593.87794.bd | DOI Listing |
Mil Med
January 2025
Combat Paramedic Program, U.S. Army MedCoE, JBSA Fort Sam Houston, TX 78234, USA.
The combat medic (68W) will play a critical role in medical operations in the event of future large-scale combat operations (LSCOs). However, the combat medic is largely not prepared for LSCOs. The revised Medical Education and Demonstration of Individual Competence (TC 8-800) state 68Ws much be able to provide advanced airway and trauma management, medication administration, and advanced casualty movement.
View Article and Find Full Text PDFJ Clin Med
December 2024
Anesthesiology and Operative Intensive Care, Faculty of Medicine, University of Augsburg, 86156 Augsburg, Germany.
Mediastinal mass syndrome represents a major threat to respiratory and cardiovascular integrity, with difficult evidence-based risk stratification for interdisciplinary management. We conducted a narrative review concerning risk stratification and difficult airway management of patients presenting with a large mediastinal mass. This is supplemented by a case report illustrating our individual approach for a patient presenting with a subtotal tracheal stenosis due to a large cyst of the thyroid gland.
View Article and Find Full Text PDFInt J Emerg Med
January 2025
Department of Emergency Medicine, Wake Forest Baptist Medical Center, 475 Vine Street, Winston-Salem, NC, 27101, USA.
Background: Angiotensin-converting enzyme inhibitors (ACEI) are the most common cause of drug-induced angioedema in the United States. Our primary objective was to provide descriptive evidence regarding emergency department (ED) disposition of ACEI-induced angioedema patients. Our secondary objective was to evaluate unique patterns in those with ACEI-induced angioedema at a tertiary referral center, including demographics, details of those requiring intubation, length of inpatient stay, and allergy documentation.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Anesthesiology, Yanbian University Hospital, Yanji, Jilin, P.R. China.
Rationale: Patients with atrial fibrillation and a large goiter have high perioperative risks and often cannot tolerate general anesthesia, making it necessary for us to explore new safe and effective anesthesia methods.
Patient Concerns: The patient presented with atrial fibrillation accompanied by rapid ventricular rate, a thrombus attached to the left atrial appendage, and a massive thyroid goiter compressing the airway.
Diagnosis: After the left humerus fracture surgery, the patient's internal fixation loosened and fractured, accompanied by infection, formation of sinus tracts, and suppuration.
J Virol
January 2025
Microbiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Measles virus (MeV) is a highly contagious respiratory virus transmitted via aerosols. To understand how MeV exits the airways of an infected host, we use unpassaged primary cultures of human airway epithelial cells (HAE). MeV typically remains cell-associated in HAE and forms foci of infection, termed infectious centers, by directly spreading cell-to-cell.
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