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A mesorectal incidentaloma: Rare localization of Castleman disease (Case report).
Exp Ther Med
April 2022
General Surgery Department, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Incidentalomas are defined as tumors or pseudo-tumoral masses accidentally discovered during clinical and imaging investigations. We present a 51-year-old female patient who presented at the gynecology service for genital bleeding caused by uterine fibromatosis. Computerized pelvic tomography showed an engorged uterus completely deformed by numerous intramural and submucosal nodular structures suggestive of multiple fibroids.
View Article and Find Full Text PDFRituximab as an effective therapeutic option in refractory Neuro-Behçet syndrome.
J Neuroimmunol
June 2020
Multiple sclerosis and Demyelinating disorders Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Head of Neurology Department National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Introduction: Behçet's disease (BD) is an inflammatory disease of unknown etiology with periods of relapses and remissions. Neuro-Behçet syndrome (NBS) is one of the main causes of long-term morbidity and mortality, making its prompt recognition and early treatment fundamental to achieving a better outcome. Currently there are no treatment guidelines either for BS or NB, making the management of these patients particularly difficult.
View Article and Find Full Text PDF[Pulmonary histoplasmosis in an immunocompetent patient].
Rev Mal Respir
May 2020
Service de pneumologie CHU de Pointe-à-pitre/Abymes, route de chauvel, BP 465, 97159 Pointe-à-Pitre, Guadeloupe, France.
Introduction: Acute pulmonary histoplasmosis (APH) is rare in an immunocompetent patient. We report a case of APH diagnosed by culture of broncho-alveolar lavage (BAL) in a patient presenting a pseudo-tumoral form with nodules progressing to cavitation.
Observation: A 41 year-old male smoker was hospitalized with a persistent fever, dry cough and dyspnoea on exertion.
Tardive Reactivation of Progressive Multiple Sclerosis During Treatment with Biotin.
Neurol Ther
June 2020
Department of Neurology, Reference Centre for Adult Leukodystrophies, Montpellier University Hospital, Montpellier, France, Montpellier, France.
Multiple sclerosis (MS) is a common autoimmune disease of the central nervous system, causing neurological disability in young adults. A growing understanding of its immunopathogenesis has led to an expanding array of therapies. Notable new advances in disease-modifying therapies for relapsing forms of multiple sclerosis that are based on anti-inflammatory activity have recently been developed.
View Article and Find Full Text PDFFulminant multifocal relapse in a fingolimod-treated multiple sclerosis patient.
Mult Scler Relat Disord
September 2019
Department of Neurosciences, Division of Neurology, Geneva University Hospital, Geneva, Switzerland; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Electronic address:
Background: Fingolimod is the first approved oral disease-modifying treatment for relapsing-remitting multiple sclerosis. Fingolimod targets lymphocytes, exerting a modulator effect on cell-surface sphingosine-1-phosphate receptors and thus blocking lymphocytes egression from secondary lymphoid organs. Recent reports describe fingolimod cessation being followed by severe or pseudo-tumoral relapse, but it usually does not happen on continuous long-term treatment.
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