Several surgical procedures and photodynamic therapy (PDT) for the treatment of choroidal neovascularization (CNV) in age-related macular degeneration (ARMD) and their advantages, disadvantages and complications were reviewed. It is important to establish an evaluating system and taking science attitude to survey various novel surgical procedures, to evaluate their clinical results, with emphasis on the limited safety and restriction of indication.
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Am J Ophthalmol Case Rep
March 2025
Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan.
Purpose: To describe a case of an elderly woman who presented with acute choroidal elevation, and the elevation disappeared without any treatment a month after the onset.
Observation: A 64-year-old woman presented to the clinic with complaint of blurred vision in her left eye. Her left visual acuity was 20/32 and choroidal elevation in the macular and subretinal fluid of the left eye was observed with optical coherence tomography (OCT), and no abnormalities in her right eye.
Am J Ophthalmol Case Rep
March 2025
Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Purpose: To report a case of bilateral choroidal osteoma successfully treated with subscleral sclerectomy for secondary serous retinal detachment (SRD).
Observations: A 52-year-old Japanese woman first diagnosed with Vogt-Koyanagi-Harada disease and treated with steroids for 9 years was referred to our clinic. SRD in both eyes recurred frequently and was uncontrolled with adalimumab subcutaneous injections and oral cyclosporine, in addition to steroids.
Semin Ophthalmol
January 2025
Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Purpose: Standardized data collection is needed to improve research for rare diseases. In this manuscript, we describe our experience establishing the Prospective Ocular Tumor Study (POTS).
Methods: The ongoing POTS captures all patients with an ocular tumor seen on the Ocular Oncology Service at Mayo Clinic Rochester and collects patient demographics, tumor features, treatment, and outcomes.
Photodiagnosis Photodyn Ther
January 2025
Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. Electronic address:
Purpose: Bietti crystalline dystrophy (BCD) is a rare retinal dystrophy characterized by progressive visual impairment. This study aimed to evaluate changes in retinal and choroidal vessels and blood flow in BCD patients using swept-source optical coherence tomography angiography (SS-OCTA) and to investigate potential parameters associated with visual function.
Methods: This cross-sectional study included 166 eyes from 86 clinically diagnosed BCD patients, classified into three disease stages based on Yuzawa's classification.
J Bioinform Syst Biol
January 2024
Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 73104, United States.
Purpose: Nitric oxide (NO) is recognized as an important biological mediator that controls several physiological functions, and evidence is now emerging that this molecule may play a significant role in the postnatal control of ocular growth and myopia development. We therefore sought to understand the role that nitric oxide plays in visually-guided ocular growth in order to gain insight into the underlying mechanisms of this process.
Methods: Choroids were incubated in organ culture in the presence of the NO donor, PAPA- NONOate (1.
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