Objective: To study the differences of clinical characteristics between patients with extraovarian peritoneal serous papillary carcinoma (EPSPC) and those with papillary serous ovarian carcinoma (PSOC).
Methods: Fourteen patients with EPSPC and 50 patients with PSOC who were admitted to Peking Union Medical College Hospital from 1984 to 2002 were retrospectively analyzed, and their clinical features, chemosensitivities and survival rate were compared.
Results: Patients with EPSPC were significantly older than those with PSOC (mean age 62.7 years versus 53.6 years, P < 0.01). The chemo-resistant rate (83%) in EPSPC was significantly higher than that (38%) of the PSOC (P < 0.05). The 1-, 2-, and 3-year survival rates (72%, 10%, 0%) in the EPSPC were significantly lower than those (95%, 79%, 62%) of the PSOC (P < 0.05).
Conclusion: EPSPC are likely to occur in older women, have higher chemo-resistance and poorer prognosis compared with PSOC.
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