A series of pyrimidyl-5-hydroxamic acids was prepared for evaluation as inhibitors of histone deacetylase (HDAC). Amino-2-pyrimidinyl can be used as a linker to provide HDAC inhibitors of good enzymatic potency.
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| http://dx.doi.org/10.1016/j.ejmech.2005.01.008 | DOI Listing |
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