Objective: To study the effects of high frequency vibration on expression of myosin heavy chain (MHC) in intrafusal and extrafusal fibers in soleus muscles of tail-suspended rats.
Method: Weightlessness was simulated by tail suspension of female rats. Using immunohistochemistry technique, changes of expression of MHC in intrafusal and extrafusal fibers of soleus muscles were detected.
Result: Expression of fast MHC in intrafusal and extrafusal fibers of soleus muscles increased during 7 d of simulated weightlessness, whereas during 7 d of tail suspension plus high frequency vibration, these changes were not detected.
Conclusion: High frequency vibration can counteract the changes in expression of MHC in intrafusal and extrafusal fibers of rats soleus under muscles of rats in simulated weightlessness situation.
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