The studies of 39 highly skilled sambo wrestlers and 60 medical students from a study group ascertained that the dietary levels of iron in the students going in for sports was close to the physiological requirements in winter; it was twice less than the normal values. The daily balance of iron was negative. The trend of blood iron levels was pronouncedly seasonal. The maximum concentrations of iron in plasma and formed blood elements were noted in all the students in autumn and the minimum ones were observed in spring and especially summer months. At almost all stages of an all-year-round follow-up, the levels of iron in the plasma was lower while those in the formed elements were higher in the sportsmen than those in the untrained students. The immunological responsiveness changes largely depended on the season rather than the students' motor activity. At almost all the stages of the follow-up, the concentrations of T and B lymphocytes, phagocytic parameters, and the number of circulating immune complexes were significantly higher in highly skilled sportsmen than in the untrained students.
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Science
January 2025
Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA, USA.
Influenza virus pandemics and seasonal epidemics have claimed countless lives. Recurrent zoonotic spillovers of influenza viruses with pandemic potential underscore the need for effective countermeasures. In this study, we show that pre-exposure prophylaxis with broadly neutralizing antibody (bnAb) MEDI8852 is highly effective in protecting cynomolgus macaques from severe disease caused by aerosolized highly pathogenic avian influenza H5N1 virus infection.
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January 2025
Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
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View Article and Find Full Text PDFCurr Rheumatol Rep
January 2025
Division of Rheumatology, Department of Pediatrics, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA.
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Front Immunol
January 2025
College of Fisheries, Key Lab of Freshwater Animal Breeding, Ministry of Agriculture, Huazhong Agricultural University, Wuhan, Hubei, China.
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View Article and Find Full Text PDFClin Cosmet Investig Dermatol
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College of Life Science, Shihezi University, Shihezi, Xinjiang, People's Republic of China.
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