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Individualized Treatment of Multiple Magnetic Foreign Body Ingestion in Children.

J Laparoendosc Adv Surg Tech A

January 2025

Department of General Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

The incidence of multiple magnetic foreign body (MMFB) ingestion in children is rising, which poses a serious risk for gastrointestinal tract injury. In the current study, the clinical characteristics were analyzed to enhance awareness among parents and caregivers, treatment experiences were summarized and discussed, and optimal treatment plans were identified. A retrospective analysis was performed on 130 pediatric patients with MMFB ingestion at the Children's Hospital Affiliated with Zhejiang University School of Medicine, between June 2016 and June 2023.

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Importance: This article highlights key National Institutes of Health (NIH) programs, policies, and scientific advances that have informed and improved the health of women and describe the promise and potential of harnessing cutting-edge science and integrative approaches to advance women's health research. Policy updates combined with recent scientific and programmatic initiatives are intended to expand understanding of women's health, deliver diagnostics, and develop preventive approaches and novel therapies to meet critical health needs of contemporary women.

Observations: To benefit all people through the work funded and conducted by the NIH biomedical research enterprise, NIH has implemented policies that broadly expanded the knowledge of human health and disease from the laboratory to the clinic.

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Association of radiation-induced normal tissue toxicity with a high genetic risk for rheumatoid arthritis.

J Natl Cancer Inst

January 2025

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, The Christie NHS Foundation Trust, Manchester, United Kingdom.

Purpose: Overlapping genes are involved with rheumatoid arthritis (RA) and DNA repair pathways. Therefore, we hypothesised that patients with a high polygenic risk score (PRS) for RA will have an increased risk of radiotherapy (RT) toxicity given the involvement of DNA repair.

Methods: Primary analysis was performed on 1494 prostate cancer, 483 lung cancer and 1820 breast cancer patients assessed for development of RT toxicity in the REQUITE study.

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Development and Testing of an Objective Structured Clinical Examination for Evaluating Nurses in Infusion Therapy.

J Infus Nurs

December 2024

Author Affiliations: School of Nursing (Mss Meszaros, de Almeida, and Aoki; Drs Silva and Lima), Vascular Access and Infusion Therapy Team, Clinical Hospital (Ms Vieira), Vascular Access and Infusion Therapy Team, Women's Hospital Professor Doutor José Aristodemo Pinotti (Ms Castelani), State University of Campinas (UNICAMP), São Paulo, Brazil; Nursing Department (Dr Oliveira-Kumakura), Health Faculty of the Paris City University, Paris, France.

This study aimed to develop, assess, and test an Objective Structured Clinical Examination (OSCE) to evaluate nurses' competency in planning and managing infusion therapy. The study adopted a methodological approach with a quantitative design and was conducted from December 2020 to August 2021 at a university hospital in São Paulo, Brazil. Data collection occurred in 3 stages: development of scenarios and assessment checklists, evaluation of expert consensus, and testing scenarios with the target audience.

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