Objective: Tumoral growth is an angiogenesis-dependent event. Although there are studies about the importance of histopathologic angiogenesis in various malignancies, the assessment of the angiogenesis by radiologic techniques is not well established. The aim of this study was to investigate the efficacy of echo contrast-enhanced power Doppler ultrasonography (PDUS) in determining the angiogenic status of renal cell carcinoma (RCC).
Methods: Power Doppler ultrasonography was performed before and after intravenous administration of an echo contrast agent in 42 patients with renal masses. Twenty-one of these renal masses were diagnosed as RCC histopathologically, and these 21 patients were reevaluated retrospectively. The color pixel ratios of selected images were calculated as the ratio of the number of pixels showing power Doppler signals to the total number of pixels within the lesion. The results were compared with the histopathologic microvessel density (MVD).
Results: A significant correlation was found between color pixel ratio and MVD values in both PDUS techniques. The use of the echo contrast agent improved this correlation and P values (Spearman rho from 0.436 to 0.551; P from .048 to .01).
Conclusions: Color pixel ratio values reflect the MVD in RCC. Therefore, these results suggest that preoperative quantification of angiogenesis can be possible with the help of PDUS in RCC.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.7863/jum.2005.24.6.747 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessment of uterine caruncles, uterine cervix, and vulva during the postpartum period in Kivircik ewes with shear-wave elastography.
Front Vet Sci
December 2024
Department of Anatomy, Faculty of Veterinary Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Introduction: This study aims to quantify the shear wave speed (SWS) and stiffness of the uterine cervix (close to the internal cervical ostium (IOC) which is the cranial portion of cervix and close to the external cervical ostium (EOC) which is the caudal portion of cervix), caruncular areas, and vulvar labia during the postpartum period in healthy Kivircik ewes by using shear-wave elastography. Power Doppler ultrasonography was performed to evaluate the color pixel percentage (CPP) of the caruncles.
Methods: The study included 13 healthy pregnant Kivircik ewes, which were randomly selected.
Ultrafast Coherence-Based Power Doppler Estimation Using Nonlinear Compounding With Complementary Subset Transmit.
Ultrasound Med Biol
January 2025
Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Objective: Conventional coherent plane wave compounding (CPWC) and sum-of-square power Doppler (PD) estimation lead to low contrast and high noise level in ultrafast PD imaging when the number of plane-wave angle and the ensemble length is limited. The coherence-based PD estimation using temporal-multiply-and-sum (TMAS) of high-lag autocorrelation can effectively suppress the uncorrelated noises but at the cost of signal power due to the blood flow decorrelation.
Methods: In this study, the TMAS PD estimation is incorporated with complementary subset transmit in nonlinear compounding (DMAS-CST) to leverage the signal coherence in both angular and temporal dimensions for improvement of PD image quality.
The maternal body mass index and first-trimester placental (vascular) development.
Placenta
December 2024
Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. Electronic address:
Background: Maternal obesity is associated with maternal complications, including hypertensive disorders of pregnancy (HDP), and related fetal complications, such as fetal growth restriction. During pregnancy, the placenta is one of the key regulators of embryonic and fetal growth. Previous studies mainly investigated placental growth by measuring postpartum placental weight.
View Article and Find Full Text PDFThe predictive value of anti-IFI16 antibodies for the development or persistence of digital ulcers in systemic sclerosis.
Clin Rheumatol
January 2025
Department of Rheumatology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai, 200040, China.
To evaluate the association of anti-IFI16 antibodies with peripheral vasculopathy and the predictive value of anti-IFI16 antibodies for the development or persistence of digital ulcers (DPDU) in SSc. A total of 42 SSc patients and 42 age- and sex-matched healthy controls were enrolled. Anti-IFI16 antibodies were examined by ELISA.
View Article and Find Full Text PDFUsefulness of Aortic Valve Calcification in Patients With Low-Flow Aortic Stenosis.
Circ Cardiovasc Imaging
January 2025
Department of Cardiology, Odense University Hospital, Denmark (N.S.B.M., J.S.D., M.A., A.H., R.C.-S., J.E.M., K.A.Ø., M.-A.C.).
Background: Aortic valve calcification (AVC) has been shown to be a powerful assessment of aortic stenosis (AS) severity and a predictor of adverse outcomes. However, its accuracy in patients with low-flow AS has not yet been proven. The objective of the study was to assess the predictive value of AVC in patients with classical low-flow (CLF, that is, low-flow reduced left ventricular ejection fraction) or paradoxical low-flow (PLF, that is, low-flow preserved left ventricular ejection fraction) AS.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!