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| http://dx.doi.org/10.1055/s-2003-43329 | DOI Listing |
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Perianal leiomyosarcoma as a rare sequela of rectal cancer radiotherapy: a case report.
Front Oncol
November 2024
Department of Pathology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang, Guangdong, China.
Radiation-induced sarcomas (RIS) are iatrogenic malignancies that arise following high-dose radiotherapy, posing a significant clinical challenge due to their poor prognosis and resistance to conventional treatments. The incidence of RIS is increasing with advancements in radiotherapy techniques. This report presents a case of a 71-year-old male diagnosed with stage III rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and curative surgery.
View Article and Find Full Text PDFPost radiotherapy femoral head avascular necrosis.
Radiol Case Rep
October 2024
Department of Oncology, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Osteonecrosis is the death of bone cells due to insufficient blood supply; radiotherapy for various underlying malignancies is one of the uncommon causes. Microvascular damage or underlying tissue fibrosis, which leads to an ischemic environment and cell death, is a proposed mechanism. Factors influencing risk of radiation induced AVN include type of radiation whether external beam radiotherapy or brachytherapy, age of the patient, included body part and concomitant additional steroid or chemotherapy treatment.
View Article and Find Full Text PDFOutcome improvement with chemotherapy and radiotherapy in primary, localized, radiation-associated angiosarcoma of the breast region: a retrospective case series analysis.
ESMO Open
June 2024
Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano.
Background: We report on a series of consecutive patients with localized radiation-associated angiosarcoma (RAAS) of the breast region (BR) treated at two Italian sarcoma reference centers.
Materials And Methods: We retrospectively reviewed all cases of primary, localized, resectable RAAS of the BR, treated at one of the two participating institutions from 2000 to 2019. Relapse-free survival (RFS) and overall survival (OS) were calculated.
[Radiation-induced parotid leiomyosarcoma].
Ann Pathol
May 2024
Service d'anatomie et cytologie pathologiques, Inserm UMR 1253 I-brain, CHRU de Tours, université François-Rabelais de Tours, 2, boulevard Tonnellé, 37044 Tours, France; Faculté de médecine de Tours, université François-Rabelais de Tours, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours, France; House Institute Foundation, Los Angeles, CA 90057, États-Unis.
Introduction: First case of radiation-induced parotid leiomyosarcoma.
Anatomo-clinical Observation: A 50-year-old woman with a history of cervical irradiation for Hodgkin's lymphoma presented with a right parotid tumefaction. Examination noted a deep adherent pretragal mass with peripheral facial palsy.
Lung cavitation to pneumothorax: A case report of the multilayered respiratory challenges in oncology patients.
Int J Surg Case Rep
January 2024
Northeast Georgia Medical Center, Graduate Medical Education, Research Department, United States of America. Electronic address:
Introduction: The management of patients with complex oncological histories poses unique challenges, particularly when they are on targeted chemotherapy agents known for specific side effects. This case report illuminates the multifaceted complexities encountered in such scenarios, with a focus on the rare complications associated with targeted therapies.
Case Presentation: We present a 50-year-old male with an extensive oncological background, including childhood retinoblastoma and radiation-induced leiomyosarcoma.
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