The authors prospectively studied the value of clinical and neurophysiologic measurements in assessing progression in ALS. Motor unit number estimation (MUNE) and the neurophysiologic index (NI) were significantly correlated with ADM strength (maximal voluntary isometric contraction force in the abductor digiti minimi muscle [MVIC-ADM]). MUNE and the NI were reliable, but the NI showed a lower variation. On assessing progression at 3, 6, and 12 months, MUNE, NI, and MVIC-ADM showed the highest rate of change. The NI is a potentially useful new neurophysiologic measurement.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1212/01.WNL.0000162036.76024.AB | DOI Listing |
Publication Analysis
Top Keywords
progression als
8
assessing progression
8
quantitating progression
4
als authors
4
authors prospectively
4
prospectively studied
4
studied clinical
4
clinical neurophysiologic
4
neurophysiologic measurements
4
measurements assessing
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!