The aim of the study was to evaluate the efficiency of different methods of preventive treatment considering the incidence of regional metastases and survival rate in squamous cell carcinoma of oral cavity. 139 patients were evaluated who were treated at the National Center of Oncology during 1985-2002. According to study results, the following was concluded: the preventive treatment is reasonable in mentioned tumors for regional control, which allows decrease of regional metastases incidence and improves the 2-year survival rates; the surgical method is most preferable among the preventive methods of treatment. Using this method, the metastases were found in clinically negative neck in 37,5%, it decreases the incidence of metastases to 21,9% and raises the 2-year survival rate to 69,0%.

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