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Successful Multi-Modal Laser Intervention and Histopathological Evaluation of Multiple Glomangiomas.
Lasers Surg Med
December 2024
Department of Dermatology, Veterans Health Administration, San Antonio, Texas, USA.
Objectives: Glomangiomas are benign vascular malformations that exist within the spectrum of glomuvenous malformations which consist of varying amounts of glomus cells, vascular spaces, and smooth muscle. Glomangiomas are often treated due to associated pain, particularly when located on pressure areas such as the back or extensor surfaces, which can cause difficulty with certain activities and occupational functions. Histologically glomangiomas consist of prominent dilated vascular spaces lined by glomus cells typically situated in the deep-dermis to subcutaneous fat which limits treatment to modalities capable of reaching the depth of the tumor including excision, sclerotherapy, and laser therapy.
View Article and Find Full Text PDFFeasibility of an indocyanine green-hyaluronic acid mixture (LuminoMark™) for targeting suspicious axillary lymph nodes in patients with breast cancer.
BMC Cancer
December 2024
Department of Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Purpose: During breast cancer surgery, the use of dyes such as indigo carmine, methylene blue, or indocyanine green (ICG) for targeting axillary lymph nodes (ALNs) under ultrasound guidance can result in rapid diffusion, complicated tissue differentiation, and disruption of staining. LuminoMark™, a novel ICG-hyaluronic acid mixture, can provide real-time visualization and minimize dye spread, thereby ensuring a clear surgical field. The aim of our study was to evaluate the efficacy of LuminoMark™ for targeting ALNs in patients with breast cancer.
View Article and Find Full Text PDFBiopolymer chitosan-capped yttrium and cobalt dual-doped SnO as an advanced biodegradable photocatalyst for efficient organic pollutant degradation.
Int J Biol Macromol
December 2024
Department of Chemistry, University of Ulsan, Ulsan 44610, Republic of Korea. Electronic address:
The improper handling and uncontrolled discharge of toxic organic dyes result in significant adverse effects on both human health and the environment. This study investigates the fabrication of SnO₂, yttrium and cobalt dual-doped SnO₂ (YCSn), chitosan-capped SnO₂ (CS*Sn), and chitosan-capped yttrium and cobalt dual-doped SnO₂ (CS*YCSn) nanoparticles using a one-step coprecipitation method for the photocatalytic degradation of methylene blue (MB) under visible light irradiation. Characterization techniques including X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), high-resolution transmission electron microscopy (HRTEM), and ultraviolet-visible (UV-Vis) spectrophotometry confirm the successful synthesis of biodegradable CS*YCSn nanoparticles.
View Article and Find Full Text PDFPEGylated iron oxide-gold core-shell nanoparticles for tumor-targeted delivery of Rapamycin.
3 Biotech
January 2025
Department of Biotechnology, University of Calicut, Kerala Malappuram, 673635 India.
Rapamycin analogs are approved by the FDA for breast and renal cancer treatment. Hence, the possibility of nanoparticle-mediated delivery of Rapamycin could be examined. In the present study, PEGylated Gold-core shell iron oxide nanoparticles were used for the targeted delivery of Rapamycin, and R-Au-IONPs were formulated.
View Article and Find Full Text PDFResazurin dye is an in vivo sensor of kidney tubular function.
Kidney Int
December 2024
Division of Pharmaceutics and Pharmacology, College of Pharmacy & Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA. Electronic address:
Glomerular filtration rate (GFR) is the main functional index of kidney health and disease. Currently, no methods are available to directly measure tubular mass and function. Here, we report a serendipitous finding that the in vitro cell viability dye resazurin can be used in mice as an exogenous sensor of tubular function.
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