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Dynamics search of highly magnetized blood laden with copper-gold-titania nanoparticles in a ciliary artery with catheterization and entropy.
Electromagn Biol Med
January 2025
Department of Mathematics, University of Gour Banga, Malda, India.
Biomagnetic fluid dynamics (BFD) is an emerging and promising field within fluid mechanics, focusing on the dynamics of bio-fluids like blood in the presence of magnetic fields. This research is crucial in the medical arena for applications such as medication delivery, diagnostic and therapeutic procedures, prevention of excessive bleeding, and treatment of malignant tumors using magnetic particles. This study delves into the intricacies of blood flow induced by cilia, carrying trihybrid nanoparticles (gold, copper, and titania), within a catheterized arterial annulus under a robust magnetic field.
View Article and Find Full Text PDFDeformation mechanism and damage energy evolution of coal body under different gas pressures based on the energy principle.
Sci Rep
January 2025
College of Mining, Liaoning Technical University, Fuxin, 123000, Liaoning, China.
With increasing mining depth, the coal pillars of a coal mine will be in a stressful environment characterized by high gas pressures and unidirectional loading. To investigate the damage evolution characteristics and energy evolution mechanism of coal pillars loaded in a gas pressure environment, a uniaxial compression test was performed on a coal body under different gas pressures using a load testing apparatus for gas-containing coal rocks. The obtained results showed that the mechanical properties of the coal body varied with the gas pressure.
View Article and Find Full Text PDFExperimental study on modal analysis and vibration response of tunnel structures under different damage conditions due to subway train loads.
Sci Rep
January 2025
Inner Mongolia Research Institute, China University of Mining and Technology (Beijing), Ordos, 017000, China.
Based on a prototype of the Beijing subway tunnel, this research conducts large-scale model experiments to systematically investigate the vibration response patterns of tunnels with different damage levels under the influence of measured train loads. Initially, the polynomial fitting modal identification method (Levy) and the model test preparation process are introduced. Then, using time-domain peak acceleration, frequency response function, frequency-domain modal frequency, and modal shape indicators, a detailed analysis of the tunnel's dynamic response is conducted.
View Article and Find Full Text PDFSurface receptor-targeted Protein-based nanocarriers for drug delivery: Advances in cancer therapy.
Nanotechnology
January 2025
Department of Biotechnology, Kalasalingam Academy of Research and Education (Deemed to be University), Anand Nagar, School of Bio, Chemical & Process Enginneering, Krishnankoil, Krishnan Kovil, Tamil Nadu, 626126, INDIA.
Significant progress has been made in cancer therapy with protein-based nanocarriers targeted directly to surface receptors for drug delivery. The nanocarriers are a potentially effective solution for the potential drawbacks of traditional chemotherapy, such as lack of specificity, side effects, and development resistance. Peptides as nanocarriers have been designed based on their biocompatible, biodegradable, and versatile functions to deliver therapeutic agents into cancer cells, reduce systemic toxicity, and maximize therapy efficacy through utilizing targeted ligands such as antibodies, amino acids, vitamins, and other small molecules onto protein-based nanocarriers and thus ensuring that drugs selectively accumulate in the cancer cells instead of healthy organs/drug release at a target site without effects on normal cells, which inherently caused less systemic toxicity/off-target effect.
View Article and Find Full Text PDFThe Effect of Strength Training Targeting Medial Thigh Muscles on Neuromuscular and Biomechanical Risk Factors for Anterior Cruciate Ligament Injury: A Randomized Controlled Trial.
Sports Med Open
January 2025
Department of Mechanical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 04107, Republic of Korea.
Background: Knee valgus loading is thought to be an important contributor to noncontact anterior cruciate ligament (ACL) injuries, but the effects of training programs focusing on decreasing knee valgus loading on lower extremity biomechanics with respect to ACL injury risk remain unclear. Thus, this study aimed to examine the effect of strength training designed to strengthen the medial thigh muscles on lower extremity joint kinematics, kinetics and muscle activity during single-leg landing.
Methods: A total of 35 healthy participants randomly conducted either exercises targeting medial thigh muscles (intervention group) or exercises that did not target specific lower extremity muscles (control group).
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