Two cases of scleredema of Buschke are described, which occurred in pediatric age group--an uncommon occurrence after febrile illness. Both cases were self-limiting. Characteristic features are described.
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Macroglossia and lip edema: A case of paraproteinemia-associated scleredema responsive to intravenous immunoglobulins.
JAAD Case Rep
February 2024
Division of Dermatology, Montefiore Einstein, Albert Einstein College of Medicine, Bronx, New York.
Treatment of scleredema adultorum of Buschke with intravenous immunoglobulin and mycophenolate mofetil in a 14-year-old girl: a case report.
J Med Case Rep
February 2024
Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Article Synopsis
- * A case is presented involving a 14-year-old girl from Iran who experienced rapid progression of skin thickening, ruled out for malignancies and connective tissue disorders before being diagnosed with scleredema.
- * The report emphasizes the potential effectiveness of intravenous immunoglobulin and mycophenolate mofetil in treating this rare disease, despite the lack of definitive treatments available.
[Differential diagnosis of sclerosing skin diseases: scleredema adultorum of Buschke].
Dermatologie (Heidelb)
March 2024
Abteilung für translationale Dermatoinfektiologie, Westfälische Wilhelms-Universität Münster, Röntgenstr. 21, 48149, Münster, Deutschland.
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- Scleredema adultorum of Buschke is a condition characterized by thickening of the skin, particularly starting at the neck and spreading, which can limit mobility due to increased dermal stiffness.
- Diagnosis relies on histological evidence of mucin deposits and is differentiated from other sclerosing diseases, with three subtypes linked to infections, paraproteins, or diabetes.
- Treatment includes physiotherapy and therapies like ultraviolet irradiation, along with addressing underlying conditions, particularly focusing on optimizing diabetes management to reduce insulin use.
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- - Scleredema diabeticorum (SD) is a frequent condition linked to diabetes, but treatment options are often limited and not very effective.
- - Patients with SD can suffer from troubling symptoms, including itching, burning sensations, and pain, which can significantly affect their comfort.
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