Purpose: The surgical anatomy of the human cavernous sinus has been described by several authors. A clearer understanding of the anatomy of the cavernous sinus has resulted in an increased interest in surgical approaches to this region. Regarding the anatomical concept of the cavernous sinus previous descriptions should be revised.
Methods: In our study, 35 skull-base blocks including both cavernous sinuses were investigated.
Results: There is considerable reason that the lateral wall of the cavernous sinus is covered by a "medial temporal dura layer" attached to the leptomeningeal pockets of the cranial nerves III-V1+2. There is no significant constance of the internal carotid artery within the cavernous sinus. All cranial nerves adjacent to or traversing the cavernous sinus are embedded within a leptomeningeal sheath similar to a pocket. The abducent nerve traverses a venous space, which should be named "petroclival venous confluence" rather than Dorello's canal. The extremely variable cavernous space is covered by a one-layer cell line. There is no evidence of any venous-plexus structure. Fibrose bands (trabecle) are present in different numbers.
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http://dx.doi.org/10.1016/j.aanat.2004.06.004 | DOI Listing |
J Neurosurg Pediatr
January 2025
1Neurotology Unit, Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow; and.
Objective: The objective of this study was to discuss the characteristics of intracranial extension in patients with juvenile nasopharyngeal angiofibroma (JNA) and propose and an algorithm for its management.
Methods: A retrospective chart review of all patients with JNA who underwent operations between January 2013 and January 2023 was done, and those cases with intracranial extension categorized as stage IIIb, IVa, and IVb according to the Andrews modification of the Fisch staging classification were included in the study. Data were collected about age at presentation, symptoms, radiological findings, routes of intracranial extension, therapeutic management, and follow-up.
Headache
January 2025
Bangalore Medical College and Research Institute, Bangalore, India.
Objective: This systematic review aims to consolidate and analyze the existing evidence on Tolosa-Hunt syndrome (THS) in the pediatric population, focusing on clinical features, diagnostic challenges, treatment outcomes, and prognosis.
Background: Tolosa-Hunt syndrome is a rare headache disorder caused by idiopathic inflammation of the cavernous sinus, orbital apex, or orbit, resulting in neuro-ophthalmological manifestations. It is uniquely characterized by cranial nerve palsies and often responds well to steroids.
Sci Rep
January 2025
Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Transcription factors (TFs), including steroidogenic factor-1 (SF-1), T-box transcription factor (TPIT) and pituitary transcription factor-1 (PIT-1), play a pivotal role in the cytodifferentiation of adenohypophysis. However, the impact of TFs on the growth patterns of nonfunctioning pituitary adenomas (NFPAs) remains unclear. This study aims to investigate the correlation between the expression of TFs and NFPAs growth patterns.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
January 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin300052, China.
To investigate the clinical features of Tolosa-Hunt syndrome (THS), a type of painful ophthalmoplegia. This was a retrospective case series study. The clinical data of patients diagnosed with painful ophthalmoplegia in the Department of Neurology of Tianjin Medical University General Hospital from January 2019 to December 2022 were continuously collected.
View Article and Find Full Text PDFFront Oncol
December 2024
Department of Neurosurgery, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Objective: This study aims to define a set of related anatomical landmarks based on preoperative Magnetic Resonance Imaging (MRI) of patients with pituitary adenomas (PAs). It explores the impact of the dynamic relationships between different anatomical landmarks and the tumor on the resection rate and tumor progression/recurrence during the endoscopic endonasal approach (EEA).
Methods: A single-center institutional database review was conducted, identifying patients with PAs treated with EEA from December 2018 to January 2023.
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