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An Optimal Scalp Rotation Flap Design: Mathematical and Bio-Mechanical Analysis.
JPRAS Open
March 2025
Plastic and Reconstructive Surgery Department, Alfred Health.
The design and implementation of successful rotational flaps of the scalp remains a complex process. There are several described techniques, all of which are based on a two-dimension surface, absent consideration of the convexity, and thereby three-dimensional nature of the scalp. This has contributed to flaps that are either too small or unnecessarily large in a bid to compensate.
View Article and Find Full Text PDFNon-Invasive Assessment of VEGF and Prognosis in Gastric Cancer through Radiomic Features.
Clin Transl Gastroenterol
December 2024
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
Introduction: Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with delayed diagnosis often limiting effective treatment options. This study introduces a novel, non-invasive radiomics-based approach utilizing [18F] FDG PET/CT to predict VEGF status and survival in GC patients. The ability to non-invasively assess these parameters can significantly influence therapeutic decisions and outcomes.
View Article and Find Full Text PDFExpansion of stereotactic work envelope using transformation matrices and geometric algebra for neurosurgery.
Biomed Eng Lett
January 2025
NaviNetics, Inc, Rochester, MN USA.
Stereotactic systems have traditionally used Cartesian coordinate combined with linear algebraic mathematical models to navigate the brain. Previously, the development of a novel stereotactic system allowed for improved patient comfort, reduced size, and carried through a simplified interface for surgeons. The system was designed with a work envelope and trajectory range optimized for deep brain stimulation applications only.
View Article and Find Full Text PDFThe persuasive role of generic-you in online interactions.
Sci Rep
January 2025
Department of Psychology, Bryn Mawr College, Bryn Mawr, PA, USA.
Persuasion plays a crucial role in human communication. Yet, convincing someone to change their mind is often challenging. Here, we demonstrate that a subtle linguistic device, generic-you (i.
View Article and Find Full Text PDFRevealing the impact of tadalafil-loaded proniosomal gel against dexamethasone-delayed wound healing via modulating oxido-inflammatory response and TGF-β/Macrophage activation pathway in rabbit model.
PLoS One
January 2025
Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Menoufia University, Shibin El-Kom, Egypt.
A serious challenge of the chronic administration of dexamethasone (DEX) is a delay in wound healing. Thus, this study aimed to investigate the potential of Tadalafil (TAD)-loaded proniosomal gel to accelerate the healing process of skin wounds in DEX-challenged rabbits. Skin wounds were induced in 48 rabbits of 4 groups (n = 12 per group) and skin wounds were treated by sterile saline (control), TAD-loaded proniosomal gel topically on skin wound, DEX-injected rabbits, and DEX+TAD-loaded proniosomal gel for 4 weeks.
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