The purpose of this report is to add support to the growing literature that there is a correlation between radiation and cavernomas of the brain, particularly if the radiation is received in childhood, as well as to increase awareness of this correlation in the radiology community. Retrospective review of our experience returned five patients who received radiation therapy while they were children and developed cavernomas in the irradiated tissues 3-41 years later. Cavernomas should be considered in the differential diagnosis of a hemorrhagic lesion in any patient who has received previous CNS radiation, particularly if he or she underwent radiation therapy in childhood.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158583 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Surgery of brainstem cavernous malformations: surgical nuances and outcomes of a monocentric series of 34 patients.
Neurol Sci
December 2024
Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.
Background: Brainstem cavernous malformations (BCM) constitute one of the most controversial and challenging neurological pathologies: both natural course and surgical manipulation can lead to severe neurological symptoms by direct compression or following hemorrhage of this highly eloquent brain region.
Methods: The vascular section of the prospectively collected neurosurgical database of our center (2011-2023) was retrospectively reviewed, seeking all patients operated on for a sporadic BCM. Clinical, radiological and surgical data, operative records and videos were analyzed by independent reviewers with the assistance of a dedicated neuropsychologist, blinded to the hospital course.
Pediatric Brain Stem Cavernoma: A Therapeutic Conundrum.
Stroke
December 2024
Stroke and Cerebrovascular Diseases Clinic, Neurology Department, Hospital Civil de Guadalajara Fray Antonio Alcalde, México (N.N.B.-A., N.G.-U., J.L.R.-S., A.J.-R.).
Magnetic resonance imaging findings of cerebral venous malformations.
Neurol Sci
December 2024
Faculty of Medicine, Department of Radiology, Tokat Gaziosmanpasa University, Tokat, Turkey.
Purpose: Our study aimed to evaluate the incidence and anatomical locations of cerebral venous malformations (CVMs), their alterations over time, and magnetic resonance imaging (MRI) findings of their relationships with each other in patients who underwent magnetic susceptibility-weighted imaging (SWI) and contrast-enhanced MRI.
Methods: The drainage pattern of developmental venous anomalies (DVAs), the number of collecting veins, DVA thrombosis, signal-intensity abnormalities, and hemosiderin deposits (nodular, diffuse, or both) related to the DVA, were examined. The alterations over time in cavernomas (type and size) were assessed.
Spectra of intracranial diseases in Chinese military pilots (cadets) unqualified for transfer to pilot modified high performance aircraft.
World J Radiol
November 2024
Naval Medical Center, Naval Medical University of Chinese PLA, Shanghai 200052, China.
Article Synopsis
- Cerebrovascular diseases and intracranial tumors pose significant risks to military pilots, emphasizing the need for thorough screening and early intervention to prevent inflight incapacitation.
- The study investigates the types of intracranial diseases and medical imaging findings in military pilots (cadets) undergoing physical exams for transfer to high performance aircraft, aiming to improve aeromedical support.
- Of 554 pilots examined, 36 were found with abnormal MRI results, displaying conditions such as arachnoid cysts, small aneurysms, and other issues that disqualified them from flying high-performance aircraft.
Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report.
Arterioscler Thromb Vasc Biol
January 2025
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden (M.M.O., A.N., M.D., H.S., T.M., K.G.).
Background: Cerebral cavernous malformation (CCM) is a disease characterized by vascular malformations that primarily develop in the brain. These malformations are prone to leak, and their rupture or thrombotic closure can cause life-threatening hemorrhages and strokes. Mouse models have been instrumental to study the disease, but most cause premature lethality, precluding the investigation of disease mechanisms through intravital microscopy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!