Eighty patients were submitted to orotracheal intubation with adult bullard laryngoscope blade. Use and advantages are described, especially in difficult intubation.
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Disentangling Sources of Momentum Fluctuations in Xe+Xe and Pb+Pb Collisions with the ATLAS Detector.
Phys Rev Lett
December 2024
CERN, Geneva, Switzerland.
High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.
View Article and Find Full Text PDFThe provision of echocardiography in critical care: a multi-centre survey of the UK and Crown Dependencies.
Intensive Care Med
December 2024
Department of Perioperative Medicine, Barts Health NHS Trust, London, UK.
The genomic and clinical consequences of replacing procarbazine with dacarbazine in escalated BEACOPP for Hodgkin lymphoma: a retrospective, observational study.
Lancet Oncol
January 2025
Department of Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK; Faculty of Health, Medicine, and Social Care, Anglia Ruskin University, Cambridge, UK; Department of Haematology, University of Cambridge, Cambridge, UK. Electronic address:
Background: Procarbazine-containing chemotherapy regimens are associated with cytopenias and infertility, suggesting stem-cell toxicity. When treating Hodgkin lymphoma, procarbazine in escalated-dose bleomycin-etoposide-doxorubicin-cyclophosphamide-vincristine-procarbazine-prednisolone (eBEACOPP) is increasingly replaced with dacarbazine (eBEACOPDac) to reduce toxicity. We aimed to investigate the impact of this drug substitution on the mutation burden in stem cells, patient survival, and toxicity.
View Article and Find Full Text PDFStrategies for genetic manipulation of the halotolerant black yeast : ectopic DNA integration and marker-free CRISPR/Cas9 transformation.
Microbiol Spectr
January 2025
Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.
is a halotolerant black yeast commonly found in hypersaline environments. This yeast is also the causative agent of tinea nigra, a superficial mycosis of the palm of the hand and soles of the feet of humans. In addition to their remarkable halotolerance, this black yeast exhibits an unconventional cell division cycle, alternating between fission and budding cell division.
View Article and Find Full Text PDFAn updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis.
Amyloid
December 2024
Boston University Amyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Background: Each monoclonal antibody light chain associated with AL amyloidosis has a unique sequence. Defining how these sequences drive amyloid deposition could facilitate faster diagnosis and lead to new treatments.
Methods: Light chain sequences are collected in the AL-Base repository.
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