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Role of brachytherapy in the boost management of anal carcinoma with node involvement (CORS-03 study).
Int J Radiat Oncol Biol Phys
March 2013
Department of Radiation Therapy, Institut Paoli Calmettes, Marseille, France.
Purpose: To assess retrospectively the clinical outcome in anal cancer patients, with lymph node involvement, treated with split-course radiation therapy and receiving a boost through external beam radiation therapy (EBRT) or brachytherapy (BCT).
Methods And Materials: From 2000 to 2005, among 229 patients with invasive nonmetastatic anal squamous cell carcinoma, a selected group of 99 patients, with lymph node involvement, was studied. Tumor staging reported was T1 in 4 patients, T2 in 16 patients, T3 in 49 patients, T4 in 16 patients, and T unknown in 14 patients and as N1 in 67 patients and N2/N3 in 32 patients.
A specific approach for elderly patients with head and neck cancer.
Anticancer Drugs
August 2011
Department of Radiation Oncology, Centre Hospitalier Princesse Grace, Monaco.
Approximately 10% of head and neck (HN) tumors occur in patients aged more than or equal to 80 years. In this population, the main challenge for physicians is to deal with the benefit/risk ratio of treatments and tumor-related symptoms. As elderly patients are generally excluded from clinical trials, there is a lack of evidence-based data with regard to the most appropriate multidisciplinary management.
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