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Long-term kidney outcomes in survivors of Wilms tumor: a single-center retrospective cohort study.
Pediatr Nephrol
January 2025
Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Background: Several studies have investigated long-term kidney outcomes in survivors of Wilms tumor (WT). However, many have small sample sizes, and there is a wide variation in reported outcomes. The aim of this study is to investigate the long-term kidney outcomes in survivors of WT (S-WT), including those patients considered to be at high risk for poor kidney outcomes, and using updated estimated glomerular filtration rate (eGFR) equations.
View Article and Find Full Text PDFZinner Syndrome in a Young Male: A Case Report and Review of the Literature.
Cureus
December 2024
Radiodiagnosis, MNR Medical College and Hospital, Sangareddy, IND.
Zinner syndrome is an extremely uncommon congenital anomaly of the male urogenital tract. It is attributed to an embryological anomaly that arises in the distal segment of the mesonephric or Wolffian duct. It is the inadequate migration of the ureteric bud that contributes to the failure of differentiation of the metanephric blastema, which ultimately results in ipsilateral renal agenesis and atresia of the ejaculatory duct.
View Article and Find Full Text PDFNeurological management of ischemic stroke in sickle cell disease- a case report with an updated review of the literature.
Neurol Sci
December 2024
Department of Neuroscience, Imaging, and Clinical Science, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Background: In children and adults with sickle-cell disease (SCD), acute ischemic stroke (AIS) associated with a vaso-occlusive crisis is a leading cause of physical and cognitive disability and death. However, neurological guidelines for acute management of AIS fail to directly address this issue. We here report a case of a man with severe cerebrovascular complications and illustrate the current evidence on the management of SCD-related AIS.
View Article and Find Full Text PDFAdipokines and Cardiometabolic Heart Failure with Preserved Ejection Fraction: A State-of-the-Art Review.
Diagnostics (Basel)
November 2024
Department of Cardiology & Heart Failure Outpatient Clinic, Sismanogleio-Amalia Fleming General Hospital, 14 25is Martiou Str., 15127 Melissia, Greece.
Background: Cardiometabolic heart failure with preserved ejection fraction (HFpEF) is largely driven by obesity-related factors, including adipokines and bioactive peptides primarily secreted by the adipose tissue, such as leptin, adiponectin, and resistin. These molecules link metabolic dysregulation to cardiovascular dysfunction, influencing HFpEF progression and patient outcomes Methods: A comprehensive literature search was conducted in PubMed up to 20 November 2024, using keywords and MeSH terms, such as "HFpEF", "adipokines", "leptin", "adiponectin", and "resistin", yielding 723 results. Boolean operators refined the search, and reference lists of key studies were reviewed.
View Article and Find Full Text PDFToxicological impact of copper nanoparticles on rainbow trout: hematological, biochemical, antioxidant, and histopathological responses with oxidative gene expression.
Toxicol Mech Methods
December 2024
Department of Microbiology, Graphic Era (Deemed to be University), Dehradun, Uttarrakhand, India.
Copper nanoparticles (CuNPs) are increasingly used across various industries due to their catalytic, antimicrobial, and electrical properties. However, their potential toxicity in aquatic environments, particularly to non-target organisms like fish, remains poorly understood. This study investigated the effects of CuNP exposure on rainbow trout () by comprehensively evaluating hematological, biochemical, antioxidant, molecular, and histopathological parameters.
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