Modeling vocal-fold vibration is extremely significant in realizing the vibration properties of human vocal folds and investigating their physiological and pathological characteristics. A combined model presented is two mass-finite element (T-F) model, which integrates all merits of both the finite element method (FEM) model and the asymmetric two-mass model of vocal folds. The high-speed glottis graph (HGG) can also be synthesized by the model. The result shows that T-F model can simulate the vibration behavior of normal and pathological vocal folds in a more realistic way with competitively computational speed. Therefore, the T-F model is helpful to gaining a thorough understanding of the vibration properties of vocal folds.
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Article Synopsis
- The study explored how human vocal fold fibroblasts (hVFF) interact with macrophages in the presence of cigarette smoke extract (CSE) and vibration, focusing on vocal fold inflammation.
- Researchers cultured hVFF with CSE, applying either static or dynamic conditions, and then measured various mRNA and protein levels to assess inflammation.
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