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A Qualitative Study on the Experiences of Patients with Pulmonary Hypertension Undergoing Polypharmacy.
Br J Hosp Med (Lond)
December 2024
Department of Nursing, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Pulmonary hypertension (PH) is a severe progressive disease characterized by elevated blood pressure in the lungs. Medications are a critical form of treatment for patients with PH. This study aims to explore the experiences of patients with PH undergoing polypharmacy, thereby providing a more concrete foundation for formulating targeted intervention measures.
View Article and Find Full Text PDFImpact of fluorination on membrane-protein stabilization and extraction by lactobionamide detergents.
Chempluschem
January 2025
Kaiserslautern University of Technology: Rheinland-Pfalzische Technische Universitat Kaiserslautern-Landau, Chemistry, 67663, Kaiserslautern, GERMANY.
We report the synthesis of a series of detergents with a lactobionamide polar head group and a tail containing four to seven perfluorinated carbon atoms. Critical micellar concentrations (CMCs) were determined using isothermal titration calorimetry (ITC) and surface tension (SFT) measurements, showing a progressive decrease from 27 mM to about 0.2 mM across the series.
View Article and Find Full Text PDFAn Innovative Method of Improving an Extract of from Leaves: Its Anticancer Effect Involves the Cell Endoplasmic Reticulum.
Int J Mol Sci
January 2025
Department of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.
In this manuscript, the effects of two extracts from were tested: (a) an extract titrated to 49.7% of andrographolide and obtained from leaves of the plant: (b) the pure andrographolide titrated to 99%. The extracts were dissolved in 1-butanol and tested on tumor lines (MCF7 and SH-SY5Y) and the non-tumor line (Huvec) to understand the effects on cell proliferation.
View Article and Find Full Text PDFPreparation of Novel Slow-Release Acid Materials for Oilfield Development via Encapsulation.
Materials (Basel)
December 2024
Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.
Acid-fracturing technology has been applied to form pathways between deep oil/gas resources and oil production pipelines. The acid fracturing fluid is required to have special slow-release performance, with no acidity at low temperatures, while steadily generating acid at high temperatures underground. At present, commercial acid systems in oilfields present problems such as the uncontrollable release effect, high costs, and significant pollution.
View Article and Find Full Text PDFDevelopment of colorimetric and fluorescent closed tube LAMP assay using simplified extraction for diagnosis of Meloidogyne enterolobii in root tissues.
Sci Rep
January 2025
Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
Meloidogyne enterolobii, a guava root-knot nematode, is a highly virulent pest in tropical and subtropical regions causing galls or knots in roots of diverse plant species posing a serious threat to agriculture. Managing this nematode is challenging due to limitations in conventional identification based on isolation and microscopic classification requiring expertise and time. A colorimetric and fluorescent LAMP assay using simplified extraction method targeting rDNA-ITS region was developed to detect M.
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