[Concentration of hydrochloric acid and pepsin in gastric juice in dogs after starvation and refeeding].

Feeding fogs with meat after a 3-day period of starvation increased hydrochloric acid concentration with subsequent return of the parameter to normal values. Under the same conditions, pepsin concentration decreased and raised up after re-feeding. Histamine administration following the starvation decreased hydrochloric acid concentration with subsequent normalising. In three days after re-feeding and histamine administration, pepsin concentration drooped owing, probably, to a decrease of parietal cell H2-receptor affinity to histamine. Pentagastrin administration after the starvation increased hydrochloric acid concentration. The findings suggest G-cell function inhibition occurring after a 3-day starvation which is important for the stomach mucous membrane protection.