AI Article Synopsis
- This report highlights the first two documented cases of mediastinal granuloma caused by histoplasmosis in Brazil, emphasizing diagnostic aspects.
- Tissue samples were collected through mediastinoscopy and thoracotomy, confirming the presence of histoplasmosis in both patients.
- The second case involved complications, including erosion of a calcified mass into the bronchial tree, leading to bilateral aspiration pneumonitis, underscoring the importance of considering histoplasmosis in differential diagnoses for granulomas, especially with significant calcifications.
Article Abstract
This report documents the first two Brazilian cases of mediastinal granuloma due to histoplasmosis, presenting selected aspects on the diagnosis. Tissue samples revealing histoplasmosis were obtained from each of the patients by mediastinoscopy and thoracotomy. In the second patient, a subcarinal calcified mass eroded into the bronchial tree, leading to secondary bilateral aspiration pneumonitis one week after thoracotomy. Although rare, histoplasmosis should be included in the differential diagnosis of mediastinal granuloma, specially if there are calcifications greater than 10 mm in dimension.
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| http://dx.doi.org/10.1590/s0036-46652005000200009 | DOI Listing |
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