AI Article Synopsis
- Researchers created libraries of heterocyclic compounds for testing new agrochemicals using a common chemical intermediate.
- A total of 18 different libraries were successfully made with varying yields.
- Some compounds from these libraries showed promising activity, particularly in screening for fungicides.
Article Abstract
Heterocyclic demonstration libraries for agrochemical screening were prepared from the common intermediates 2-methoxy-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles (1), using standard solution-phase techniques. A total of 18 screening libraries were prepared in good to excellent yields. Several members of these libraries were active in the first level of agrochemical screening, especially in the fungicide screen.
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| http://dx.doi.org/10.1021/cc049828y | DOI Listing |
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