This study investigates the Salmonella effector protein SopA. We show that in Salmonella enterica serovar Dublin-infected cells, SopA(1-347) fused to two carboxy-terminal hemagglutinin tags partially colocalized with mitochondria. Transfection of eukaryotic cells with a panel of constructs encoding truncated versions of SopA identified that amino acids 100 to 347 were sufficient to target SopA to the mitochondria.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112013 | PMC |
| http://dx.doi.org/10.1128/JB.187.10.3565-3571.2005 | DOI Listing |
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