AI Article Synopsis
- Researchers have developed new inhibitors for protein tyrosine phosphatase-1B (PTP1B) using a method called structure-based design.
- These inhibitors feature a specific chemical structure known as 1,2,5-thiadiazolidin-3-one-1,1-dioxide.
- This discovery could lead to advancements in treatments related to PTP1B, which is important in various biological processes.
Article Abstract
Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.
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| http://dx.doi.org/10.1016/j.bmcl.2005.03.068 | DOI Listing |
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