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Technology usage and glycaemic outcomes in a single tertiary centre with an ethnically diverse and socioeconomically deprived cohort of children with type 1 diabetes mellitus.
Front Clin Diabetes Healthc
January 2025
Department of Endocrinology and Diabetes, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom.
Background: The UK National Paediatric Diabetes Audit (NPDA) data reports disparities in Haemoglobin A1c (HbA1c) levels among children and young people (CYP) with Type 1 Diabetes (T1D), with higher levels in those of Black ethnic background and lower socioeconomic status who have less access to technology. We investigate HbA1c differences in a T1D cohort with higher than national average technology uptake where > 60% come from an ethnic minority and/or socioeconomically deprived population.
Design & Methods: Retrospective cross-sectional study investigating the influence of demographic factors, technology use, and socioeconomic status (SES) on glycaemic outcomes.
Label-free imaging flow cytometry for cell classification based directly on multiple off-axis holographic projections.
J Biomed Opt
January 2025
Tel Aviv University, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv, Israel.
Significance: Imaging flow cytometry allows highly informative multi-point cell analysis for biological assays and medical diagnosis. Rapid processing of the imaged cells during flow allows real-time classification and sorting of the cells. Off-axis holography enables imaging flow cytometry without chemical cell staining but requires digital processing to the optical path delay profile for each frame before the cells can be classified, which slows down the overall processing throughput.
View Article and Find Full Text PDFFrequency and Predictors of Conversion From Laparoscopic to Open Cholecystectomy: A Single-Center Observational Study.
Cureus
December 2024
General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Objective: The study aimed to investigate the rate of conversion from laparoscopic cholecystectomy (LC) to open cholecystectomy (OC) in our population and determine the potential risk factors associated with it. Understanding these factors helps surgeons predict complex cases and plan surgeries, reducing patient risks and improving outcomes.
Methodology: A cross-sectional observational study was conducted from June 1, 2022, to May 31, 2023, at Hayatabad Medical Complex, Peshawar, on 349 patients undergoing elective LC.
Wurmb Extract Recovered Compromised Immune Status Induced by Forced Swimming in a Mouse Model.
J Microbiol Biotechnol
December 2024
Food Functionality Research Division, Korea Food Research Institute (KFRI), Wanju 55365, Republic of Korea.
Wurmb is known to contain large amounts of polyphenols and flavonoids with antioxidative and anti-inflammatory effects. However, the biological and physiological functions of have not been scientifically investigated. Thus, we investigated the immunomodulatory effect of hot water extract (YSK-N) in mice using an immune compromised model established by forced swimming (FS).
View Article and Find Full Text PDFAssociation between white blood cell count and coronary artery bypass graft failure: an individual patient data analysis of clinical trials.
J Cardiothorac Surg
January 2025
Department of Cardiothoracic Surgery, Weill Cornell Medicine, 525 E 68th St, New York, NY, 10065, USA.
Background: Baseline systemic inflammation is associated with worse long-term outcomes after coronary artery bypass grafting [CABG], but the mechanisms of this association are unclear. This study aims to explore the association between pre-operative white blood cell [WBC] count and CABG graft failure.
Methods: We pooled individual patient data from two randomized clinical trials with systematic CABG graft imaging.
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